PDB entry 3bce

View 3bce on RCSB PDB site
Description: Crystal structure of the ErbB4 kinase
Class: transferase
Keywords: active conformation, ATP-binding, Glycoprotein, Kinase, Membrane, Nucleotide-binding, Phosphorylation, Receptor, Transferase, Transmembrane, Tyrosine-protein kinase
Deposited on 2007-11-12, released 2008-02-12
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.198
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Receptor tyrosine-protein kinase erbB-4
    Species: Homo sapiens [TaxId:9606]
    Gene: ERBB4, HER4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3bcea_
  • Chain 'B':
    Compound: Receptor tyrosine-protein kinase erbB-4
    Species: Homo sapiens [TaxId:9606]
    Gene: ERBB4, HER4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3bceb_
  • Chain 'C':
    Compound: Receptor tyrosine-protein kinase erbB-4
    Species: Homo sapiens [TaxId:9606]
    Gene: ERBB4, HER4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3bcec_
  • Heterogens: MN, PG4, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3bceA (A:)
    gtapnqaqlrilketelkrvkvlgsgafgtvykgiwvpegetvkipvaikilnettgpka
    nvefmdealimasmdhphlvrllgvclsptiqlvtqlmphgclleyvhehkdnigsqlll
    nwcvqiakgmmyleerrlvhrdlaarnvlvkspnhvkitdfglarllegdekeynadggk
    mpikwmalecihyrkfthqsdvwsygvtiwelmtfggkpydgiptreipdllekgerlpq
    ppictidvymvmvkcwmidadsrpkfkelaaefsrmardpqrylviqgddrmklpspnds
    kffqnlldeedledmmdaeeylvpqafn
    

    Sequence, based on observed residues (ATOM records): (download)
    >3bceA (A:)
    tapnqaqlrilketelkrvkvlgsgafgtvykgiwvpegetvkipvaikilnetpkanve
    fmdealimasmdhphlvrllgvclsptiqlvtqlmphgclleyvhehkdnigsqlllnwc
    vqiakgmmyleerrlvhrdlaarnvlvkspnhvkitdfglarllegdekeynagkmpikw
    malecihyrkfthqsdvwsygvtiwelmtfggkpydgiptreipdllekgerlpqppict
    idvymvmvkcwmidadsrpkfkelaaefsrmardpqrylviqgdd
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3bceB (B:)
    gtapnqaqlrilketelkrvkvlgsgafgtvykgiwvpegetvkipvaikilnettgpka
    nvefmdealimasmdhphlvrllgvclsptiqlvtqlmphgclleyvhehkdnigsqlll
    nwcvqiakgmmyleerrlvhrdlaarnvlvkspnhvkitdfglarllegdekeynadggk
    mpikwmalecihyrkfthqsdvwsygvtiwelmtfggkpydgiptreipdllekgerlpq
    ppictidvymvmvkcwmidadsrpkfkelaaefsrmardpqrylviqgddrmklpspnds
    kffqnlldeedledmmdaeeylvpqafn
    

    Sequence, based on observed residues (ATOM records): (download)
    >3bceB (B:)
    tapnqaqlrilketelkrvkvlgsgafgtvykgiwvpegetvkipvaikilnetkanvef
    mdealimasmdhphlvrllgvclsptiqlvtqlmphgclleyvhehkdnigsqlllnwcv
    qiakgmmyleerrlvhrdlaarnvlvkspnhvkitdfglarllegdekeynagkmpikwm
    alecihyrkfthqsdvwsygvtiwelmtfggkpydgiptreipdllekgerlpqppicti
    dvymvmvkcwmidadsrpkfkelaaefsrmardpqrylviqgddrm
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >3bceC (C:)
    gtapnqaqlrilketelkrvkvlgsgafgtvykgiwvpegetvkipvaikilnettgpka
    nvefmdealimasmdhphlvrllgvclsptiqlvtqlmphgclleyvhehkdnigsqlll
    nwcvqiakgmmyleerrlvhrdlaarnvlvkspnhvkitdfglarllegdekeynadggk
    mpikwmalecihyrkfthqsdvwsygvtiwelmtfggkpydgiptreipdllekgerlpq
    ppictidvymvmvkcwmidadsrpkfkelaaefsrmardpqrylviqgddrmklpspnds
    kffqnlldeedledmmdaeeylvpqafn
    

    Sequence, based on observed residues (ATOM records): (download)
    >3bceC (C:)
    tapnqaqlrilketelkrvkvlgsgafgtvykgiwvpegetvkipvaikilnettgpkan
    vefmdealimasmdhphlvrllgvclsptiqlvtqlmphgclleyvhehkdnigsqllln
    wcvqiakgmmyleerrlvhrdlaarnvlvkspnhvkitdfglarlledekeynadgkmpi
    kwmalecihyrkfthqsdvwsygvtiwelmtfggkpydgiptreipdllekgerlpqppi
    ctidvymvmvkcwmidadsrpkfkelaaefsrmardpqrylviqgd