PDB entry 3bce

View 3bce on RCSB PDB site
Description: Crystal structure of the ErbB4 kinase
Class: transferase
Keywords: active conformation, ATP-binding, Glycoprotein, Kinase, Membrane, Nucleotide-binding, Phosphorylation, Receptor, Transferase, Transmembrane, Tyrosine-protein kinase
Deposited on 2007-11-12, released 2008-02-12
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.198
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Receptor tyrosine-protein kinase erbB-4
    Species: Homo sapiens [TaxId:9606]
    Gene: ERBB4, HER4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3bcea_
  • Chain 'B':
    Compound: Receptor tyrosine-protein kinase erbB-4
    Species: Homo sapiens [TaxId:9606]
    Gene: ERBB4, HER4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3bceb_
  • Chain 'C':
    Compound: Receptor tyrosine-protein kinase erbB-4
    Species: Homo sapiens [TaxId:9606]
    Gene: ERBB4, HER4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3bcec_
  • Heterogens: MN, PG4, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3bceA (A:)
gtapnqaqlrilketelkrvkvlgsgafgtvykgiwvpegetvkipvaikilnettgpka
nvefmdealimasmdhphlvrllgvclsptiqlvtqlmphgclleyvhehkdnigsqlll
nwcvqiakgmmyleerrlvhrdlaarnvlvkspnhvkitdfglarllegdekeynadggk
mpikwmalecihyrkfthqsdvwsygvtiwelmtfggkpydgiptreipdllekgerlpq
ppictidvymvmvkcwmidadsrpkfkelaaefsrmardpqrylviqgddrmklpspnds
kffqnlldeedledmmdaeeylvpqafn

    Sequence, based on observed residues (ATOM records): (download) 
    >3bceA (A:)
tapnqaqlrilketelkrvkvlgsgafgtvykgiwvpegetvkipvaikilnetpkanve
fmdealimasmdhphlvrllgvclsptiqlvtqlmphgclleyvhehkdnigsqlllnwc
vqiakgmmyleerrlvhrdlaarnvlvkspnhvkitdfglarllegdekeynagkmpikw
malecihyrkfthqsdvwsygvtiwelmtfggkpydgiptreipdllekgerlpqppict
idvymvmvkcwmidadsrpkfkelaaefsrmardpqrylviqgdd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3bceB (B:)
gtapnqaqlrilketelkrvkvlgsgafgtvykgiwvpegetvkipvaikilnettgpka
nvefmdealimasmdhphlvrllgvclsptiqlvtqlmphgclleyvhehkdnigsqlll
nwcvqiakgmmyleerrlvhrdlaarnvlvkspnhvkitdfglarllegdekeynadggk
mpikwmalecihyrkfthqsdvwsygvtiwelmtfggkpydgiptreipdllekgerlpq
ppictidvymvmvkcwmidadsrpkfkelaaefsrmardpqrylviqgddrmklpspnds
kffqnlldeedledmmdaeeylvpqafn

    Sequence, based on observed residues (ATOM records): (download) 
    >3bceB (B:)
tapnqaqlrilketelkrvkvlgsgafgtvykgiwvpegetvkipvaikilnetkanvef
mdealimasmdhphlvrllgvclsptiqlvtqlmphgclleyvhehkdnigsqlllnwcv
qiakgmmyleerrlvhrdlaarnvlvkspnhvkitdfglarllegdekeynagkmpikwm
alecihyrkfthqsdvwsygvtiwelmtfggkpydgiptreipdllekgerlpqppicti
dvymvmvkcwmidadsrpkfkelaaefsrmardpqrylviqgddrm

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3bceC (C:)
gtapnqaqlrilketelkrvkvlgsgafgtvykgiwvpegetvkipvaikilnettgpka
nvefmdealimasmdhphlvrllgvclsptiqlvtqlmphgclleyvhehkdnigsqlll
nwcvqiakgmmyleerrlvhrdlaarnvlvkspnhvkitdfglarllegdekeynadggk
mpikwmalecihyrkfthqsdvwsygvtiwelmtfggkpydgiptreipdllekgerlpq
ppictidvymvmvkcwmidadsrpkfkelaaefsrmardpqrylviqgddrmklpspnds
kffqnlldeedledmmdaeeylvpqafn

    Sequence, based on observed residues (ATOM records): (download) 
    >3bceC (C:)
tapnqaqlrilketelkrvkvlgsgafgtvykgiwvpegetvkipvaikilnettgpkan
vefmdealimasmdhphlvrllgvclsptiqlvtqlmphgclleyvhehkdnigsqllln
wcvqiakgmmyleerrlvhrdlaarnvlvkspnhvkitdfglarlledekeynadgkmpi
kwmalecihyrkfthqsdvwsygvtiwelmtfggkpydgiptreipdllekgerlpqppi
ctidvymvmvkcwmidadsrpkfkelaaefsrmardpqrylviqgd