PDB entry 3bbc
View 3bbc on RCSB PDB site
Description: Crystal structure of R88A mutant of the NM23-H2 transcription factor
Class: transferase
Keywords: transcriptional factor, kinase, NM23 gen, hexamer, cancer, Activator, Anti-oncogene, ATP-binding, Cell cycle, DNA-binding, Magnesium, Metal-binding, Nucleotide metabolism, Nucleotide-binding, Nucleus, Phosphorylation, Transcription regulation, Transferase
Deposited on
2007-11-09, released
2008-09-23
The last revision prior to the SCOPe 2.08 freeze date was dated
2010-08-04, with a file datestamp of
2010-07-30.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.176
AEROSPACI score: 0.56
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Nucleoside diphosphate kinase B
Species: Homo sapiens [TaxId:9606]
Gene: NME2, NM23B
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3bbca_ - Chain 'B':
Compound: Nucleoside diphosphate kinase B
Species: Homo sapiens [TaxId:9606]
Gene: NME2, NM23B
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3bbcb_ - Chain 'C':
Compound: Nucleoside diphosphate kinase B
Species: Homo sapiens [TaxId:9606]
Gene: NME2, NM23B
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3bbcc_ - Chain 'D':
Compound: Nucleoside diphosphate kinase B
Species: Homo sapiens [TaxId:9606]
Gene: NME2, NM23B
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3bbcd_ - Chain 'E':
Compound: Nucleoside diphosphate kinase B
Species: Homo sapiens [TaxId:9606]
Gene: NME2, NM23B
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3bbce_ - Chain 'F':
Compound: Nucleoside diphosphate kinase B
Species: Homo sapiens [TaxId:9606]
Gene: NME2, NM23B
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3bbcf_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>3bbcA (A:)
anlertfiaikpdgvqrglvgeiikrfeqkgfrlvamkflraseehlkqhyidlkdrpff
pglvkymnsgpvvamvweglnvvktgavmlgetnpadskpgtirgdfciqvgrniihgsd
svksaekeislwfkpeelvdykscahdwvye
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3bbcB (B:)
anlertfiaikpdgvqrglvgeiikrfeqkgfrlvamkflraseehlkqhyidlkdrpff
pglvkymnsgpvvamvweglnvvktgavmlgetnpadskpgtirgdfciqvgrniihgsd
svksaekeislwfkpeelvdykscahdwvye
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>3bbcC (C:)
anlertfiaikpdgvqrglvgeiikrfeqkgfrlvamkflraseehlkqhyidlkdrpff
pglvkymnsgpvvamvweglnvvktgavmlgetnpadskpgtirgdfciqvgrniihgsd
svksaekeislwfkpeelvdykscahdwvye
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>3bbcD (D:)
anlertfiaikpdgvqrglvgeiikrfeqkgfrlvamkflraseehlkqhyidlkdrpff
pglvkymnsgpvvamvweglnvvktgavmlgetnpadskpgtirgdfciqvgrniihgsd
svksaekeislwfkpeelvdykscahdwvye
- Chain 'E':
Sequence; same for both SEQRES and ATOM records: (download)
>3bbcE (E:)
anlertfiaikpdgvqrglvgeiikrfeqkgfrlvamkflraseehlkqhyidlkdrpff
pglvkymnsgpvvamvweglnvvktgavmlgetnpadskpgtirgdfciqvgrniihgsd
svksaekeislwfkpeelvdykscahdwvye
- Chain 'F':
Sequence; same for both SEQRES and ATOM records: (download)
>3bbcF (F:)
anlertfiaikpdgvqrglvgeiikrfeqkgfrlvamkflraseehlkqhyidlkdrpff
pglvkymnsgpvvamvweglnvvktgavmlgetnpadskpgtirgdfciqvgrniihgsd
svksaekeislwfkpeelvdykscahdwvye