PDB entry 3bae

View 3bae on RCSB PDB site
Description: Crystal structure of Fab WO2 bound to the N terminal domain of Amyloid beta peptide (1-28)
Class: immune system
Keywords: Abeta, amyloid beta peptide, Fab, WO2, alzheimer's disease, immunotherapies, APP, IMMUNE SYSTEM
Deposited on 2007-11-07, released 2008-04-15
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.59 Å
R-factor: 0.209
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Amyloid Beta Peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3BAE
  • Chain 'H':
    Compound: WO2 IgG2a Fab fragment Heavy Chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 3BAE
    Domains in SCOPe 2.02: d3baeh1
  • Chain 'L':
    Compound: WO2 IgG2a Fab fragment Light Chain Kappa
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 3BAE (0-217)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >3baeH (H:)
evtlkesgpgllkpsqtlsltcsfsgfsirtskvgvswirqpsgkglewlahiywdddkr
ynpslesrltiskdtsrdmvfmkitsvdtadtatyycarrgfygrkyevnhfdywgqgtt
ltvssakttapsvyplapvcgdttgssvtlgclvkgyfpepvtltwnsgslssgvhtfpa
vlqsdlytlsssvtvtsstwpsesitcnvahpasstkvdkkivprdcg

    Sequence, based on observed residues (ATOM records): (download) 
    >3baeH (H:)
vtlkesgpgllkpsqtlsltcsfsgfsirtskvgvswirqpsgkglewlahiywdddkry
npslesrltiskdtsrdmvfmkitsvdtadtatyycarrgfygrkyevnhfdywgqgttl
tvssakttapsvyplaptgssvtlgclvkgyfpepvtltwnsgslssgvhtfpavlqsdl
ytlsssvtvtsstwpsesitcnvahpasstkvdkkivpr

  • Chain 'L':
    No sequence available.