PDB entry 3b99

View 3b99 on RCSB PDB site
Description: Crystal structure of zebrafish prostacyclin synthase (cytochrome P450 8A1) in complex with substrate analog U51605
Class: isomerase
Keywords: prostacyclin synthase, cytochrome p450 8A1, CYP8A1, substrate analog-enzyme complex, ISOMERASE
Deposited on 2007-11-03, released 2007-11-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-07-04, with a file datestamp of 2012-06-29.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.218
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Prostaglandin I2 synthase
    Species: Danio rerio [TaxId:7955]
    Gene: PGIS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3b99a_
  • Chain 'B':
    Compound: Prostaglandin I2 synthase
    Species: Danio rerio [TaxId:7955]
    Gene: PGIS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3b99b_
  • Heterogens: HEM, U51, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3b99A (A:)
makktssvlygrrtrrrneppldkgmipwlghalefgkdaakfltrmkekhgdiftvraa
glyitvlldsncydavlsdvasldqtsyaqvlmkrifnmilpshnpesekkraemhfqga
sltqlsnsmqnnlrllmtpsemglktsewkkdglfnlcysllfktgyltvfgaennnsaa
ltqiyeefrrfdkllpklarttvnkeekqiasaareklwkwltpsgldrkpreqswlgsy
vkqlqdegidaemqrramllqlwvtqgnagpaafwvmgyllthpealravreeiqggkhl
rleerqkntpvfdsvlwetlrltaaalitrdvtqdkkiclsngqeyhlrrgdrlcvfpfi
spqmdpqihqqpemfqfdrflnadrtekkdffkngarvkypsvpwgtednlcpgrhfavh
aikelvftiltrfdvelcdknatvplvdpsrygfgilqpagdleiryrirfhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3b99A (A:)
rrtrrrneppldkgmipwlghalefgkdaakfltrmkekhgdiftvraaglyitvlldsn
cydavlsdvasldqtsyaqvlmkrifnmilpshnpesekkraemhfqgasltqlsnsmqn
nlrllmtpsemglktsewkkdglfnlcysllfktgyltvfgaennnsaaltqiyeefrrf
dkllpklarttvnkeekqiasaareklwkwltpsgldrkpreqswlgsyvkqlqdegida
emqrramllqlwvtqgnagpaafwvmgyllthpealravreeiqntpvfdsvlwetlrlt
aaalitrdvtqdkkiclsngqeyhlrrgdrlcvfpfispqmdpqihqqpemfqfdrflna
tekkdffkngarvkypsvpwgtednlcpgrhfavhaikelvftiltrfdvelcdknatvp
lvdpsrygfgilqpagdleiryrir

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3b99B (B:)
makktssvlygrrtrrrneppldkgmipwlghalefgkdaakfltrmkekhgdiftvraa
glyitvlldsncydavlsdvasldqtsyaqvlmkrifnmilpshnpesekkraemhfqga
sltqlsnsmqnnlrllmtpsemglktsewkkdglfnlcysllfktgyltvfgaennnsaa
ltqiyeefrrfdkllpklarttvnkeekqiasaareklwkwltpsgldrkpreqswlgsy
vkqlqdegidaemqrramllqlwvtqgnagpaafwvmgyllthpealravreeiqggkhl
rleerqkntpvfdsvlwetlrltaaalitrdvtqdkkiclsngqeyhlrrgdrlcvfpfi
spqmdpqihqqpemfqfdrflnadrtekkdffkngarvkypsvpwgtednlcpgrhfavh
aikelvftiltrfdvelcdknatvplvdpsrygfgilqpagdleiryrirfhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3b99B (B:)
rrtrrrneppldkgmipwlghalefgkdaakfltrmkekhgdiftvraaglyitvlldsn
cydavlsdvasldqtsyaqvlmkrifnmilpshnpesekkraemhfqgasltqlsnsmqn
nlrllmtpsemwkkdglfnlcysllfktgyltvftqiyeefrrfdkllpklartekqias
aareklwkwltswlgsyvkqlqdegidaemqrramllqlwvtqgnagpaafwvmgyllth
pealravreeiqntpvfdsvlwetlrltaaalitrdvtqdkkiclsngqeyhlrrgdrlc
vfpfispqmdpqihqqpemfqfdrflnadrtekkdffkngarvkypsvpwgtednlcpgr
hfavhaikelvftiltrfdvelcdknatvplvdpsrygfgilqpagdleiryrir