PDB entry 3b7r

View 3b7r on RCSB PDB site
Description: Leukotriene A4 Hydrolase Complexed with Inhibitor RB3040
Class: hydrolase
Keywords: transition state, analogue peptide, hydrolysis, alternative splicing, cytoplasm, hydrolase, leukotriene biosynthesis, metal-binding, metalloprotease, multifunctional enzyme, protease, zinc
Deposited on 2007-10-31, released 2008-09-16
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.81 Å
R-factor: 0.15
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'L':
    Compound: Leukotriene A-4 hydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: LTA4H, LTA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3b7rl1, d3b7rl2, d3b7rl3
  • Heterogens: ZN, YB, IMD, BIR, HOH

PDB Chain Sequences:

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >3b7rL (L:)
hhhhhhpeivdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvl
dtkdltiekvvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssa
lqwltpeqtsgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsair
dgetpdpedpsrkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayef
setesmlkiaedlggpyvwgqydllvlppsfpyggmenpcltfvtptllagdkslsnvia
heishswtgnlvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvk
tfgethpftklvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekf
syksittddwkdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqr
witakeddlnsfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnsei
rfrwlrlciqskwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkas
mhpvtamlvgkdlkvd

    Sequence, based on observed residues (ATOM records): (download) 
    >3b7rL (L:)
peivdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdlt
iekvvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwltp
eqtsgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetpd
pedpsrkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetesm
lkiaedlggpyvwgqydllvlppsfpyggmenpcltfvtptllagdkslsnviaheishs
wtgnlvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfgeth
pftklvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksit
tddwkdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitake
ddlnsfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwlr
lciqskwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvta
mlvgkdlkvd