PDB entry 3b7l

View 3b7l on RCSB PDB site
Description: Human farnesyl diphosphate synthase complexed with MG and minodronate
Class: transferase
Keywords: ISOPRENOID PATHWAY, CHOLESTEROL SYNTHESIS, BISPHOSPHONATE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, Cholesterol biosynthesis, Host-virus interaction, Isoprene biosynthesis, Lipid synthesis, Steroid biosynthesis, Sterol biosynthesis, Transferase
Deposited on 2007-10-31, released 2007-11-13
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.171
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Farnesyl pyrophosphate synthetase
    Species: Homo sapiens [TaxId:9606]
    Gene: FDPS, FPS, KIAA1293
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3b7la_
  • Heterogens: MG, M0N, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3b7lA (A:)
ghmmngdqnsdvyaqekqdfvqhfsqivrvltedemghpeigdaiarlkevleynaiggk
ynrgltvvvafrelveprkqdadslqrawtvgwcvellqafflvaddimdssltrrgqic
wyqkpgvgldaindanlleaciyrllklycreqpyylnlielflqssyqteigqtldllt
apqgnvdlvrftekryksivkyktafysfylpiaaamymagidgekehanakkillemge
ffqiqddyldlfgdpsvtgkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaek
varvkalyeeldlpavflqyeedsyshimalieqyaaplppavflglarkiykrrk

    Sequence, based on observed residues (ATOM records): (download) 
    >3b7lA (A:)
dvyaqekqdfvqhfsqivrvltedemghpeigdaiarlkevleynaiggkynrgltvvva
frelveprkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvgld
aindanlleaciyrllklycreqpyylnlielflqssyqteigqtldlltapqgnvdlvr
ftekryksivkyktafysfylpiaaamymagidgekehanakkillemgeffqiqddyld
lfgdpsvtgkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaekvarvkalyee
ldlpavflqyeedsyshimalieqyaaplppavflglarkiyk