PDB entry 3b7k

View 3b7k on RCSB PDB site
Description: Human Acyl-coenzyme A thioesterase 12
Class: hydrolase
Keywords: Hotdog fold, Structural Genomics, Structural Genomics Consortium, SGC, Fatty acid metabolism, Hydrolase, Lipid metabolism, Serine esterase
Deposited on 2007-10-31, released 2007-11-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acyl-coenzyme A thioesterase 12
    Species: Homo sapiens [TaxId:9606]
    Gene: ACOT12, CACH, CACH1, STARD12
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WYK0 (23-End)
      • expression tag (21-22)
    Domains in SCOPe 2.08: d3b7ka1, d3b7ka2, d3b7ka3
  • Chain 'B':
    Compound: Acyl-coenzyme A thioesterase 12
    Species: Homo sapiens [TaxId:9606]
    Gene: ACOT12, CACH, CACH1, STARD12
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3b7kb1, d3b7kb2
  • Chain 'C':
    Compound: Acyl-coenzyme A thioesterase 12
    Species: Homo sapiens [TaxId:9606]
    Gene: ACOT12, CACH, CACH1, STARD12
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WYK0 (23-End)
      • expression tag (22)
    Domains in SCOPe 2.08: d3b7kc1, d3b7kc2, d3b7kc3
  • Heterogens: COA

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3b7kA (A:)
mhhhhhhssgvdlgtenlyfqsmgevvmsqaiqpahatargelsagqllkwidttaclaa
ekhagvscvtasvddiqfeetarvgqvitikakvtrafstsmeisikvmvqdmltgiekl
vsvafstfvakpvgkekihlkpvtllteqdhvehnlaaerrkvrlqhedtfnnlmkessk
fddlifdeeegavstrgtsvqsielvlpphanhhgntfggqimawmetvatisasrlcwa
hpflksvdmfkfrgpstvgdrlvftaivnntfqtcvevgvrveafdcqewaegrgrhins
afliynaaddkenlitfpriqpiskddfrryrg

    Sequence, based on observed residues (ATOM records): (download) 
    >3b7kA (A:)
smgevvmsqaiqpahatargelsagqllkwidttaclaaekhagvscvtasvddiqfeet
arvgqvitikakvtrafstsmeisikvmvqdmltgieklvsvafstfvakpvgkihlkpv
tllteqdhvehnlaaerrkvrlqhedtrgtsvqsielvlpphanhhgntfggqimawmet
vatisasrlcwahpflksvdmfkfrgpstvgdrlvftaivnntfqtcvevgvrveafdcq
ewaegrgrhinsafliynaaddkenli

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3b7kB (B:)
mhhhhhhssgvdlgtenlyfqsmgevvmsqaiqpahatargelsagqllkwidttaclaa
ekhagvscvtasvddiqfeetarvgqvitikakvtrafstsmeisikvmvqdmltgiekl
vsvafstfvakpvgkekihlkpvtllteqdhvehnlaaerrkvrlqhedtfnnlmkessk
fddlifdeeegavstrgtsvqsielvlpphanhhgntfggqimawmetvatisasrlcwa
hpflksvdmfkfrgpstvgdrlvftaivnntfqtcvevgvrveafdcqewaegrgrhins
afliynaaddkenlitfpriqpiskddfrryrg

    Sequence, based on observed residues (ATOM records): (download) 
    >3b7kB (B:)
vvmsqaiqpahatargelsagqllkwidttaclaaekhagvscvtasvddiqfeetarvg
qvitikakvtrafstsmeisikvmvqdmltgieklvsvafstfvakpvihlkpvtllteq
dhvehnlaaerrkvrlqhedgtsvqsielvlpphanhhgntfggqimawmetvatisasr
lcwahpflksvdmfkfrgpstvgdrlvftaivnncvevgvrveafdcqewaegrgrhins
afliyna

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3b7kC (C:)
mhhhhhhssgvdlgtenlyfqsmgevvmsqaiqpahatargelsagqllkwidttaclaa
ekhagvscvtasvddiqfeetarvgqvitikakvtrafstsmeisikvmvqdmltgiekl
vsvafstfvakpvgkekihlkpvtllteqdhvehnlaaerrkvrlqhedtfnnlmkessk
fddlifdeeegavstrgtsvqsielvlpphanhhgntfggqimawmetvatisasrlcwa
hpflksvdmfkfrgpstvgdrlvftaivnntfqtcvevgvrveafdcqewaegrgrhins
afliynaaddkenlitfpriqpiskddfrryrg

    Sequence, based on observed residues (ATOM records): (download) 
    >3b7kC (C:)
mgevvmsqaiqpahatargelsagqllkwidttaclaaekhagvscvtasvddiqfeeta
rvgqvitikakvtrafstsmeisikvmvqdmltgieklvsvafstfvakpvgkekihlkp
vtllteqdhvehnlaaerrkvrlqhtsvqsielvlpphanhhgntfggqimawmetvati
sasrlcwahpflksvdmfkfrgpstvgdrlvftaivnntfqtcvevgvrveafdcqewae
grgrhinsafliyna