PDB entry 3b75

View 3b75 on RCSB PDB site
Description: Crystal Structure of Glycated Human Haemoglobin
Class: transport protein, oxygen binding
Keywords: hemoglobin, glycation, R state, R2 state, Acetylation, Disease mutation, Glycoprotein, Heme, Iron, Metal-binding, Oxygen transport, Polymorphism, Transport, Hypotensive agent, Pyruvate, S-nitrosylation, Vasoactive, TRANSPORT PROTEIN, OXYGEN BINDING
Deposited on 2007-10-30, released 2008-10-14
The last revision prior to the SCOP 1.75 freeze date was dated 2008-10-14, with a file datestamp of 2008-10-10.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.249
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Hemoglobin subunit alpha
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P69905 (0-140)
• Chain 'B':
  Compound: Hemoglobin subunit beta
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P68871 (0-145)
  Domains in SCOP 1.75: d3b75b1
• Chain 'C':
  Compound: Hemoglobin subunit alpha
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P69905 (0-140)
• Chain 'D':
  Compound: Hemoglobin subunit beta
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P68871 (0-145)
  Domains in SCOP 1.75: d3b75d1
• Chain 'E':
  Compound: Hemoglobin subunit alpha
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P69905 (0-140)
• Chain 'F':
  Compound: Hemoglobin subunit beta
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P68871 (0-145)
  Domains in SCOP 1.75: d3b75f1
• Chain 'G':
  Compound: Hemoglobin subunit alpha
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P69905 (0-140)
• Chain 'H':
  Compound: Hemoglobin subunit beta
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P68871 (0-145)
  Domains in SCOP 1.75: d3b75h1
• Chain 'S':
  Compound: Hemoglobin subunit alpha
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P69905 (0-140)
• Chain 'T':
  Compound: Hemoglobin subunit beta
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P68871 (0-145)
  Domains in SCOP 1.75: d3b75t1
• Heterogens: FRU, GLC, PO4, HEM, OXY, HOH

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3b75B (B:)
  vhltpeeksavtalwgkvnvdevggealgrllvvypwtqrffesfgdlstpdavmgnpkv
  kahgkkvlgafsdglahldnlkgtfatlselhcdklhvdpenfrllgnvlvcvlahhfgk
  eftppvqaayqkvvagvanalahkyh
  

  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3b75D (D:)
  vhltpeeksavtalwgkvnvdevggealgrllvvypwtqrffesfgdlstpdavmgnpkv
  kahgkkvlgafsdglahldnlkgtfatlselhcdklhvdpenfrllgnvlvcvlahhfgk
  eftppvqaayqkvvagvanalahkyh
  

  
  
• Chain 'E':
  No sequence available.
  
  
• Chain 'F':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3b75F (F:)
  vhltpeeksavtalwgkvnvdevggealgrllvvypwtqrffesfgdlstpdavmgnpkv
  kahgkkvlgafsdglahldnlkgtfatlselhcdklhvdpenfrllgnvlvcvlahhfgk
  eftppvqaayqkvvagvanalahkyh
  

  
  
• Chain 'G':
  No sequence available.
  
  
• Chain 'H':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3b75H (H:)
  vhltpeeksavtalwgkvnvdevggealgrllvvypwtqrffesfgdlstpdavmgnpkv
  kahgkkvlgafsdglahldnlkgtfatlselhcdklhvdpenfrllgnvlvcvlahhfgk
  eftppvqaayqkvvagvanalahkyh
  

  
  
• Chain 'S':
  No sequence available.
  
  
• Chain 'T':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3b75T (T:)
  vhltpeeksavtalwgkvnvdevggealgrllvvypwtqrffesfgdlstpdavmgnpkv
  kahgkkvlgafsdglahldnlkgtfatlselhcdklhvdpenfrllgnvlvcvlahhfgk
  eftppvqaayqkvvagvanalahkyh