PDB entry 3b4v

View 3b4v on RCSB PDB site
Description: X-Ray structure of Activin in complex with FSTL3
Class: hormone regulator complex
Keywords: Ligand-inhibitor signalling complex, Cleavage on pair of basic residues, Glycoprotein, Growth factor, Hormone, Secreted, Nucleus, Proto-oncogene, HORMONE REGULATOR COMPLEX
Deposited on 2007-10-24, released 2008-09-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.48 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Inhibin beta A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: INHBA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3b4va_
  • Chain 'B':
    Compound: Inhibin beta A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: INHBA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3b4vb_
  • Chain 'C':
    Compound: follistatin-like 3
    Species: Homo sapiens [TaxId:9606]
    Gene: FSTL3, FLRG
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: follistatin-like 3
    Species: Homo sapiens [TaxId:9606]
    Gene: FSTL3, FLRG
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Inhibin beta A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: INHBA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3b4ve_
  • Chain 'F':
    Compound: Inhibin beta A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: INHBA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3b4vf_
  • Chain 'G':
    Compound: follistatin-like 3
    Species: Homo sapiens [TaxId:9606]
    Gene: FSTL3, FLRG
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: follistatin-like 3
    Species: Homo sapiens [TaxId:9606]
    Gene: FSTL3, FLRG
    Database cross-references and differences (RAF-indexed):
  • Heterogens: EDO, SO4, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3b4vA (A:)
glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

    Sequence, based on observed residues (ATOM records): (download) 
    >3b4vA (A:)
glecdkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshislsfhstvinhyr
mrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3b4vB (B:)
glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

    Sequence, based on observed residues (ATOM records): (download) 
    >3b4vB (B:)
glecgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtgsslsfhstv
inhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3b4vE (E:)
glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

    Sequence, based on observed residues (ATOM records): (download) 
    >3b4vE (E:)
glecdnicckkqffvsfkdigwndwiiapsgyhanycegecpshislsfhstvinhyrmr
ghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3b4vF (F:)
glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

    Sequence, based on observed residues (ATOM records): (download) 
    >3b4vF (F:)
glecgvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhstv
inhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.