PDB entry 3b3q

View 3b3q on RCSB PDB site
Description: Crystal structure of a synaptic adhesion complex
Class: cell adhesion
Keywords: synaptic formation, adhesion, heterophilic, protein-protein complex, calcium binding, Membrane, Transmembrane, CELL ADHESION
Deposited on 2007-10-22, released 2008-01-15
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-05-15, with a file datestamp of 2013-05-10.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.242
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nlgn1 protein
    Species: Mus musculus [TaxId:10090]
    Gene: Nlgn1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4KMN5 (Start-576)
      • engineered mutation (284)
    Domains in SCOPe 2.06: d3b3qa_
  • Chain 'B':
    Compound: Nlgn1 protein
    Species: Mus musculus [TaxId:10090]
    Gene: Nlgn1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4KMN5 (Start-576)
      • engineered mutation (284)
    Domains in SCOPe 2.06: d3b3qb_
  • Chain 'E':
    Compound: NRXN1 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: NRXN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot A4FVB9 (8-End)
      • expression tag (0-7)
    Domains in SCOPe 2.06: d3b3qe2, d3b3qe3
  • Chain 'F':
    Compound: NRXN1 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: NRXN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot A4FVB9 (8-End)
      • expression tag (0-7)
    Domains in SCOPe 2.06: d3b3qf2, d3b3qf3
  • Heterogens: NAG, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3b3qA (A:)
adphhhhhhenlyfqgqklddvdplvttnfgkirgikkelnneilgpviqflgvpyaapp
tgehrfqppeppspwsdirnatqfapvcpqniidgrlpevmlpvwftnnldvvssyvqdq
sedclylniyvpteddirdsggpkpvmvyihggsymegtgnlydgsvlasygnvivitvn
yrlgvlgflstgdqaakgnyglldliqalrwtsenigffggdplritvfgsgaggscvnl
ltlshyseglfqraiaqsgtalsswavsfqpakyarilatkvgcqvsdtvelveclqkkp
ykelvdqdvqparyhiafgpvidgdvipddpqilmeqgeflnydimlgvnqgeglkfven
ivdsddgvsasdfdfavsnfvdnlygypegkdvlretikfmytdwadrhnpetrrktlla
lftdhqwvapavatadlhsnfgsptyfyafyhhcqtdqvpawadaahgdevpyvlgipmi
gptelfpcnfskndvmlsavvmtywtnfaktgdpnqpvpqdtkfihtkpnrfeevawtry
sqkdqlylhiglkprvkehyrankvnlwlelvphlhn

    Sequence, based on observed residues (ATOM records): (download) 
    >3b3qA (A:)
dplvttnfgkirgikkelnneilgpviqflgvpyaapptgehrfqppeppspwsdirnat
qfapvcpqniidgrlpevmlpvwftnnldvvssyvqdqsedclylniyvptedggpkpvm
vyihggsymegtgnlydgsvlasygnvivitvnyrlgvlgflstgdqaakgnyglldliq
alrwtsenigffggdplritvfgsgaggscvnlltlshyseglfqraiaqsgtalsswav
sfqpakyarilatkvgcqvsdtvelveclqkkpykelvdqdvqparyhiafgpvidgdvi
pddpqilmeqgeflnydimlgvnqgeglkfvenivdsddgvsasdfdfavsnfvdnlygy
dvlretikfmytdwadrhnpetrrktllalftdhqwvapavatadlhsnfgsptyfyafy
hhcqtdqvpawadaahgdevpyvlgipmigptelfpcnfskndvmlsavvmtywtnfakt
gdpnqpvpqdfeevawtrysqkdqlylhiglkprvkehyrankvnlwlelvphlhn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3b3qB (B:)
adphhhhhhenlyfqgqklddvdplvttnfgkirgikkelnneilgpviqflgvpyaapp
tgehrfqppeppspwsdirnatqfapvcpqniidgrlpevmlpvwftnnldvvssyvqdq
sedclylniyvpteddirdsggpkpvmvyihggsymegtgnlydgsvlasygnvivitvn
yrlgvlgflstgdqaakgnyglldliqalrwtsenigffggdplritvfgsgaggscvnl
ltlshyseglfqraiaqsgtalsswavsfqpakyarilatkvgcqvsdtvelveclqkkp
ykelvdqdvqparyhiafgpvidgdvipddpqilmeqgeflnydimlgvnqgeglkfven
ivdsddgvsasdfdfavsnfvdnlygypegkdvlretikfmytdwadrhnpetrrktlla
lftdhqwvapavatadlhsnfgsptyfyafyhhcqtdqvpawadaahgdevpyvlgipmi
gptelfpcnfskndvmlsavvmtywtnfaktgdpnqpvpqdtkfihtkpnrfeevawtry
sqkdqlylhiglkprvkehyrankvnlwlelvphlhn

    Sequence, based on observed residues (ATOM records): (download) 
    >3b3qB (B:)
dplvttnfgkirgikkelnneilgpviqflgvpyaapptgehrfqppeppspwsdirnat
qfapvcpqniidgrlpevmlpvwftnnldvvssyvqdqsedclylniyvptedggpkpvm
vyihggsymegtgnlydgsvlasygnvivitvnyrlgvlgflstgdqaakgnyglldliq
alrwtsenigffggdplritvfgsgaggscvnlltlshyseglfqraiaqsgtalsswav
sfqpakyarilatkvgcqvsdtvelveclqkkpykelvdqdvqparyhiafgpvidgdvi
pddpqilmeqgeflnydimlgvnqgeglkfvenivdsddgvsasdfdfavsnfvdnlygy
dvlretikfmytdwadrhnpetrrktllalftdhqwvapavatadlhsnfgsptyfyafy
hhcqtdqvpawadaahgdevpyvlgipmigptelfpcnfskndvmlsavvmtywtnfakt
gdpnqpvpqdfeevawtrysqkdqlylhiglkprvkehyrankvnlwlelvphlhn

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3b3qE (E:)
hsafaadpghagttyifskgggqitykwppndrpstradrlaigfstvqkeavlvrvdss
sglgdylelhihqgkigvkfnvgtddiaieesnaiindgkyhvvrftrsggnatlqvdsw
pvierypagrqltifnsqatiiiggkeqgqpfqgqlsglyynglkvlnmaaendaniaiv
gnvrlvgevphhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3b3qE (E:)
hsafaadpghttyifskgggqitykwppndrpstradrlaigfstvqkeavlvrvdsssg
lgdylelhihqgkigvkfnvgtddiaieesnaiindgkyhvvrftrsggnatlqvdswpv
ierypagrqltifnsqatiiiggkeqgqpfqgqlsglyynglkvlnmaaendaniaivgn
vrlvgev

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3b3qF (F:)
hsafaadpghagttyifskgggqitykwppndrpstradrlaigfstvqkeavlvrvdss
sglgdylelhihqgkigvkfnvgtddiaieesnaiindgkyhvvrftrsggnatlqvdsw
pvierypagrqltifnsqatiiiggkeqgqpfqgqlsglyynglkvlnmaaendaniaiv
gnvrlvgevphhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3b3qF (F:)
hsafaadpghttyifskgggqitykwppndrpstradrlaigfstvqkeavlvrvdsssg
lgdylelhihqgkigvkfnvgtddiaieesnaiindgkyhvvrftrsggnatlqvdswpv
ierypagrqltifnsqatiiiggkeqgqpfqgqlsglyynglkvlnmaaendaniaivgn
vrlvgev