PDB entry 3b3a

View 3b3a on RCSB PDB site
Description: Structure of E163K/R145E DJ-1
Class: chaperone
Keywords: PARKINSON'S DISEASE, THIJ, PFPI, Chaperone, Cytoplasm, Disease mutation, Nucleus, Oncogene, Oxidation, Parkinson disease, Phosphorylation, Polymorphism, Ubl conjugation
Deposited on 2007-10-19, released 2008-01-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.183
AEROSPACI score: 0.64 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein DJ-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PARK7
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99497
      • engineered (147)
      • engineered (165)
    Domains in SCOPe 2.08: d3b3aa1, d3b3aa2
  • Heterogens: CL, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3b3aA (A:)
gshmaskralvilakgaeemetvipvdvmrragikvtvaglagkdpvqcsrdvvicpdas
ledakkegpydvvvlpggnlgaqnlsesaavkeilkeqenrkgliaaicagptallahei
gfgskvtthplakdkmmngghytysenevekdgliltsrgpgtsfkfalaivealngkev
aaqvkaplvlkd

    Sequence, based on observed residues (ATOM records): (download) 
    >3b3aA (A:)
askralvilakgaeemetvipvdvmrragikvtvaglagkdpvqcsrdvvicpdasleda
kkegpydvvvlpggnlgaqnlsesaavkeilkeqenrkgliaaicagptallaheigfgs
kvtthplakdkmmngghytysenevekdgliltsrgpgtsfkfalaivealngkevaaqv
kaplvlk