PDB entry 3b13
View 3b13 on RCSB PDB site
Description: Crystal structure of the DHR-2 domain of DOCK2 in complex with Rac1 (T17N mutant)
Class: protein binding/signaling protein
Keywords: protein-ptotein complex, lymphocyte chemotaxis, signal tansduction, guanine nucleotide exchange factor, GTPase, PROTEIN BINDING-SIGNALING PROTEIN complex
Deposited on
2011-06-24, released
2012-03-14
The last revision prior to the SCOPe 2.08 freeze date was dated
2012-03-14, with a file datestamp of
2012-03-09.
Experiment type: XRAY
Resolution: 3.01 Å
R-factor: 0.185
AEROSPACI score: 0.27
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: dedicator of cytokinesis protein 2
Species: Homo sapiens [TaxId:9606]
Gene: DOCK2, KIAA0209
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: ras-related c3 botulinum toxin substrate 1
Species: Homo sapiens [TaxId:9606]
Gene: RAC1, TC25, MIG5
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3b13b_ - Chain 'C':
Compound: dedicator of cytokinesis protein 2
Species: Homo sapiens [TaxId:9606]
Gene: DOCK2, KIAA0209
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: ras-related c3 botulinum toxin substrate 1
Species: Homo sapiens [TaxId:9606]
Gene: RAC1, TC25, MIG5
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3b13d_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3b13B (B:)
gssgssgmqaikcvvvgdgavgkncllisyttnafpgeyiptvfdnysanvmvdgkpvnl
glwdtagqedydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilv
gtkldlrddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeai
ravl
Sequence, based on observed residues (ATOM records): (download)
>3b13B (B:)
mqaikcvvvgdgavgkncllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
qedydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavl
- Chain 'C':
No sequence available.
- Chain 'D':
Sequence, based on SEQRES records: (download)
>3b13D (D:)
gssgssgmqaikcvvvgdgavgkncllisyttnafpgeyiptvfdnysanvmvdgkpvnl
glwdtagqedydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilv
gtkldlrddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeai
ravl
Sequence, based on observed residues (ATOM records): (download)
>3b13D (D:)
mqaikcvvvgdgavgkncllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
qedydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavl