PDB entry 3aw0

View 3aw0 on RCSB PDB site
Description: Structure of SARS 3CL protease with peptidic aldehyde inhibitor
Class: HYDROLASE/HYDROLASE inhibitor
Keywords: hydrolase proteinase converting, designed inhibitor, hydrolase-hydrolase inhibitor complex
Deposited on 2011-03-09, released 2011-12-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-07-01, with a file datestamp of 2015-06-26.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3C-like proteinase
    Species: SARS coronavirus [TaxId:227859]
    Gene: 1a
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0C6U8 (0-305)
      • engineered mutation (187)
    Domains in SCOPe 2.08: d3aw0a_
  • Chain 'B':
    Compound: peptide ACE-SER-ALA-VAL-LEU-HIS-H
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3AW0 (Start-4)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3aw0A (A:)
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedllir
ksnhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacyng
spsgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegk
fygpfvdiqtaqaagtdttitlnvlawlyaavingdrwflnrftttlndfnlvamkynye
pltqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvrqc
sgvtfq

  • Chain 'B':
    No sequence available.