PDB entry 3auv

View 3auv on RCSB PDB site
Description: Predicting Amino Acid Preferences in the Complementarity Determining Regions of an Antibody-Antigen Recognition Interface
Class: immune system
Keywords: sc-dsFv (disulfide-stabilized scFv), scFv, monovalent antibody, VEGF, antibody engineering, IMMUNE SYSTEM
Deposited on 2011-02-16, released 2012-02-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-04-25, with a file datestamp of 2012-04-20.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.218
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: sc-dsFv derived from the G6-Fab
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3AUV
    Domains in SCOPe 2.08: d3auva1, d3auva2
  • Chain 'B':
    Compound: sc-dsFv derived from the G6-Fab
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3AUV
    Domains in SCOPe 2.08: d3auvb1, d3auvb2
  • Chain 'C':
    Compound: sc-dsFv derived from the G6-Fab
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3AUV
    Domains in SCOPe 2.08: d3auvc1, d3auvc2
  • Chain 'D':
    Compound: sc-dsFv derived from the G6-Fab
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3AUV
    Domains in SCOPe 2.08: d3auvd1, d3auvd2
  • Chain 'E':
    Compound: sc-dsFv derived from the G6-Fab
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3AUV
    Domains in SCOPe 2.08: d3auve1, d3auve2
  • Chain 'F':
    Compound: sc-dsFv derived from the G6-Fab
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3AUV
    Domains in SCOPe 2.08: d3auvf1, d3auvf2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3auvA (A:)
gamaqpahgsgdiqmtqspsslsasvgdrvtitcrasqdvstavawyqqkpgkapklliy
sasflysgvpsrfsgsgsgtdftltisslqpedfatyycqqhyttpptfgcgtkveikgg
gggsiegrsggggsevqlvesggglvqpggslrlscaasgftisdywihwvrqapgkcle
wvagitpaggytyyadsvkgrftisadtskntaylqmnslraedtavyycarfvfflpya
mdywgqgtlvtvssasaaaggglndifeaqkiewhe

    Sequence, based on observed residues (ATOM records): (download) 
    >3auvA (A:)
diqmtqspsslsasvgdrvtitcrasqdvstavawyqqkpgkapklliysasflysgvps
rfsgsgsgtdftltisslqpedfatyycqqhyttpptfgcgtkveievqlvesggglvqp
ggslrlscaasgftisdywihwvrqapgkclewvagitpaggytyyadsvkgrftisadt
skntaylqmnslraedtavyycarfvfflpyamdywgqgtlvtvs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3auvB (B:)
gamaqpahgsgdiqmtqspsslsasvgdrvtitcrasqdvstavawyqqkpgkapklliy
sasflysgvpsrfsgsgsgtdftltisslqpedfatyycqqhyttpptfgcgtkveikgg
gggsiegrsggggsevqlvesggglvqpggslrlscaasgftisdywihwvrqapgkcle
wvagitpaggytyyadsvkgrftisadtskntaylqmnslraedtavyycarfvfflpya
mdywgqgtlvtvssasaaaggglndifeaqkiewhe

    Sequence, based on observed residues (ATOM records): (download) 
    >3auvB (B:)
gdiqmtqspsslsasvgdrvtitcrasqdvstavawyqqkpgkapklliysasflysgvp
srfsgsgsgtdftltisslqpedfatyycqqhyttpptfgcgtkveievqlvesggglvq
pggslrlscaasgftisdywihwvrqapgkclewvagitpaggytyyadsvkgrftisad
tskntaylqmnslraedtavyycarfvfflpyamdywgqgtlvtv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3auvC (C:)
gamaqpahgsgdiqmtqspsslsasvgdrvtitcrasqdvstavawyqqkpgkapklliy
sasflysgvpsrfsgsgsgtdftltisslqpedfatyycqqhyttpptfgcgtkveikgg
gggsiegrsggggsevqlvesggglvqpggslrlscaasgftisdywihwvrqapgkcle
wvagitpaggytyyadsvkgrftisadtskntaylqmnslraedtavyycarfvfflpya
mdywgqgtlvtvssasaaaggglndifeaqkiewhe

    Sequence, based on observed residues (ATOM records): (download) 
    >3auvC (C:)
gdiqmtqspsslsasvgdrvtitcrasqdvstavawyqqkpgkapklliysasflysgvp
srfsgsgsgtdftltisslqpedfatyycqqhyttpptfgcgtkveievqlvesggglvq
pggslrlscaasgftisdywihwvrqapgkclewvagitpaggytyyadsvkgrftisad
tskntaylqmnslraedtavyycarfvfflpyamdywgqgtlvtv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3auvD (D:)
gamaqpahgsgdiqmtqspsslsasvgdrvtitcrasqdvstavawyqqkpgkapklliy
sasflysgvpsrfsgsgsgtdftltisslqpedfatyycqqhyttpptfgcgtkveikgg
gggsiegrsggggsevqlvesggglvqpggslrlscaasgftisdywihwvrqapgkcle
wvagitpaggytyyadsvkgrftisadtskntaylqmnslraedtavyycarfvfflpya
mdywgqgtlvtvssasaaaggglndifeaqkiewhe

    Sequence, based on observed residues (ATOM records): (download) 
    >3auvD (D:)
gdiqmtqspsslsasvgdrvtitcrasqdvstavawyqqkpgkapklliysasflysgvp
srfsgsgsgtdftltisslqpedfatyycqqhyttpptfgcgtkveikevqlvesggglv
qpggslrlscaasgftisdywihwvrqapgkclewvagitpaggytyyadsvkgrftisa
dtskntaylqmnslraedtavyycarfvfflpyamdywgqgtlvtvs

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3auvE (E:)
gamaqpahgsgdiqmtqspsslsasvgdrvtitcrasqdvstavawyqqkpgkapklliy
sasflysgvpsrfsgsgsgtdftltisslqpedfatyycqqhyttpptfgcgtkveikgg
gggsiegrsggggsevqlvesggglvqpggslrlscaasgftisdywihwvrqapgkcle
wvagitpaggytyyadsvkgrftisadtskntaylqmnslraedtavyycarfvfflpya
mdywgqgtlvtvssasaaaggglndifeaqkiewhe

    Sequence, based on observed residues (ATOM records): (download) 
    >3auvE (E:)
gdiqmtqspsslsasvgdrvtitcrasqdvstavawyqqkpgkapklliysasflysgvp
srfsgsgsgtdftltisslqpedfatyycqqhyttpptfgcgtkveievqlvesggglvq
pggslrlscaasgftisdywihwvrqapgkclewvagitpaggytyyadsvkgrftisad
tskntaylqmnslraedtavyycarfvfflpyamdywgqgtlvtv

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3auvF (F:)
gamaqpahgsgdiqmtqspsslsasvgdrvtitcrasqdvstavawyqqkpgkapklliy
sasflysgvpsrfsgsgsgtdftltisslqpedfatyycqqhyttpptfgcgtkveikgg
gggsiegrsggggsevqlvesggglvqpggslrlscaasgftisdywihwvrqapgkcle
wvagitpaggytyyadsvkgrftisadtskntaylqmnslraedtavyycarfvfflpya
mdywgqgtlvtvssasaaaggglndifeaqkiewhe

    Sequence, based on observed residues (ATOM records): (download) 
    >3auvF (F:)
gdiqmtqspsslsasvgdrvtitcrasqdvstavawyqqkpgkapklliysasflysgvp
srfsgsgsgtdftltisslqpedfatyycqqhyttpptfgcgtkveivqlvesggglvqp
ggslrlscaasgftisdywihwvrqapgkclewvagitpaggytyyadsvkgrftisadt
skntaylqmnslraedtavyycarfvfflpyamdywgqgtlvtv