PDB entry 3aqi

View 3aqi on RCSB PDB site
Description: H240A variant of human ferrochelatase
Class: lyase
Keywords: Heme, ferrochelatase, iron homeostasis, porphyria, heme biosynthesis, protoporphyrinogen oxidase, chelatase, LYASE
Deposited on 2010-11-03, released 2012-01-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-01-25, with a file datestamp of 2012-01-20.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.174
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ferrochelatase
    Species: Homo sapiens [TaxId:9606]
    Gene: FECH
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22830
      • conflict (50)
      • engineered mutation (175)
    Domains in SCOPe 2.08: d3aqia_
  • Chain 'B':
    Compound: Ferrochelatase
    Species: Homo sapiens [TaxId:9606]
    Gene: FECH
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22830 (0-358)
      • conflict (50)
      • engineered mutation (175)
    Domains in SCOPe 2.08: d3aqib_
  • Heterogens: FES, CHD, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3aqiA (A:)
rkpktgilmlnmggpetlgdvhdfllrlfldrdlmtlpiqnklapfiakrltpkiqeqyr
rigggspikiwtskqgegmvklldelspntaphkyyigfryvhplteeaieemerdgler
aiaftqypqyscsttgsslnaiyryynqvgrkptmkwstidrwpthhlliqcfadailke
ldhfplekrsevvilfsahslpmsvvnrgdpypqevsatvqkvmerleycnpyrlvwqsk
vgpmpwlgpqtdesikglcergrknillvpiaftsdhietlyeldieysqvlakecgven
irraeslngnplfskaladlvhshiqsnelcskqltlscplcvnpvcretksfftsqql

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3aqiB (B:)
rkpktgilmlnmggpetlgdvhdfllrlfldrdlmtlpiqnklapfiakrltpkiqeqyr
rigggspikiwtskqgegmvklldelspntaphkyyigfryvhplteeaieemerdgler
aiaftqypqyscsttgsslnaiyryynqvgrkptmkwstidrwpthhlliqcfadailke
ldhfplekrsevvilfsahslpmsvvnrgdpypqevsatvqkvmerleycnpyrlvwqsk
vgpmpwlgpqtdesikglcergrknillvpiaftsdhietlyeldieysqvlakecgven
irraeslngnplfskaladlvhshiqsnelcskqltlscplcvnpvcretksfftsqql