PDB entry 3ans

View 3ans on RCSB PDB site
Description: Human soluble epoxide hydrolase in complex with a synthetic inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: hydrolase, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2010-09-08, released 2011-01-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-01-22, with a file datestamp of 2014-01-17.
Experiment type: XRAY
Resolution: 1.98 Å
R-factor: 0.221
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Epoxide hydrolase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: EPHX2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3ansa_
  • Chain 'B':
    Compound: Epoxide hydrolase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: EPHX2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3ansb_
  • Heterogens: S38, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3ansA (A:)
    mkkghhhhhhtscnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqip
    alaqagyrvlamdmkgygessappeieeycmevlckemvtfldklglsqavfighdwggm
    lvwymalfypervravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaeleq
    nlsrtfkslfrasdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksgf
    rgplnwyrnmernwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrghi
    edcghwtqmdkptevnqilikwldsdarnppvvskm
    

    Sequence, based on observed residues (ATOM records): (download)
    >3ansA (A:)
    cnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqipalaqagyrvlam
    dmkgygessappeieeycmevlckemvtfldklglsqavfighdwggmlvwymalfyper
    vravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaeleqnlsrtfkslfra
    sdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksgfrgplnwyrnmer
    nwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrghiedcghwtqmdkp
    tevnqilikwldsd
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3ansB (B:)
    mkkghhhhhhtscnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqip
    alaqagyrvlamdmkgygessappeieeycmevlckemvtfldklglsqavfighdwggm
    lvwymalfypervravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaeleq
    nlsrtfkslfrasdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksgf
    rgplnwyrnmernwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrghi
    edcghwtqmdkptevnqilikwldsdarnppvvskm
    

    Sequence, based on observed residues (ATOM records): (download)
    >3ansB (B:)
    cnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqipalaqagyrvlam
    dmkgygessappeieeycmevlckemvtfldklglsqavfighdwggmlvwymalfyper
    vravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaeleqnlsrtfkslfra
    sdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksgfrgplnwyrnmer
    nwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrghiedcghwtqmdkp
    tevnqilikwldsd