PDB entry 3an2

View 3an2 on RCSB PDB site
Description: The structure of the centromeric nucleosome containing CENP-A
Deposited on 2010-08-27, released 2011-07-20
The last revision was dated 2012-07-25, with a file datestamp of 2012-07-20.
Experiment type: XRAY
Resolution: 3.6 Å
R-factor: 0.271
AEROSPACI score: 0.06 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone H3-like centromeric protein A
    Species: Homo sapiens [TaxId:9606]
    Gene: CENPA
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: histone h4
    Species: Homo sapiens [TaxId:9606]
    Gene: H4
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Histone H2A type 1-B/E
    Species: Homo sapiens [TaxId:9606]
    Gene: H2A
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Histone H2B type 1-J
    Species: Homo sapiens [TaxId:9606]
    Gene: H2B
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Histone H3-like centromeric protein A
    Species: Homo sapiens [TaxId:9606]
    Gene: CENPA
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: histone h4
    Species: Homo sapiens [TaxId:9606]
    Gene: H4
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Histone H2A type 1-B/E
    Species: Homo sapiens [TaxId:9606]
    Gene: H2A
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Histone H2B type 1-J
    Species: Homo sapiens [TaxId:9606]
    Gene: H2B
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: 147 mer DNA
  • Chain 'J':
    Compound: 147 mer DNA

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3an2A (A:)
gshmgprrrsrkpeaprrrspsptptpgpsrrgpslgasshqhsrrrqgwlkeirklqks
thllirklpfsrlareicvkftrgvdfnwqaqallalqeaaeaflvhlfedaylltlhag
rvtlfpkdvqlarrirgleeglg

    Sequence, based on observed residues (ATOM records):
    >3an2A (A:)
gwlkeirklqksthllirklpfsrlareicvkftrgvdfnwqaqallalqeaaeaflvhl
fedaylltlhagrvtlfpkdvqlarrirg

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3an2B (B:)
gshmsgrgkggkglgkggakrhrkvlrdniqgitkpairrlarrggvkrisgliyeetrg
vlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg

    Sequence, based on observed residues (ATOM records):
    >3an2B (B:)
niqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakrktvtam
dvvyalkrqgrtlygfgg

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3an2C (C:)
gshmsgrgkqggkarakaktrssraglqfpvgrvhrllrkgnyservgagapvylaavle
yltaeilelagnaardnkktriiprhlqlairndeelnkllgrvtiaqggvlpniqavll
pkkteshhkakgk

    Sequence, based on observed residues (ATOM records):
    >3an2C (C:)
trssraglqfpvgrvhrllrkgnyservgagapvylaavleyltaeilelagnaardnkk
triiprhlqlairndeelnkllgrvtiaqggvlpniq

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3an2D (D:)
gshmpepaksapapkkgskkavtkaqkkdgkkrkrsrkesysiyvykvlkqvhpdtgiss
kamgimnsfvndiferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtk
avtkytsak

    Sequence, based on observed residues (ATOM records):
    >3an2D (D:)
esysiyvykvlkqvhpdtgisskamgimnsfvndiferiageasrlahynkrstitsrei
qtavrlllpgelakhavsegtkavtkytsa

  • Chain 'E':
    Sequence, based on SEQRES records:
    >3an2E (E:)
gshmgprrrsrkpeaprrrspsptptpgpsrrgpslgasshqhsrrrqgwlkeirklqks
thllirklpfsrlareicvkftrgvdfnwqaqallalqeaaeaflvhlfedaylltlhag
rvtlfpkdvqlarrirgleeglg

    Sequence, based on observed residues (ATOM records):
    >3an2E (E:)
lkeirklqksthllirklpfsrlareicvkffnwqaqallalqeaaeaflvhlfedayll
tlhagrvtlfpkdvqlarrirgl

  • Chain 'F':
    Sequence, based on SEQRES records:
    >3an2F (F:)
gshmsgrgkggkglgkggakrhrkvlrdniqgitkpairrlarrggvkrisgliyeetrg
vlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg

    Sequence, based on observed residues (ATOM records):
    >3an2F (F:)
dniqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakrktvta
mdvvyalkrqgrtlygfgg

  • Chain 'G':
    Sequence, based on SEQRES records:
    >3an2G (G:)
gshmsgrgkqggkarakaktrssraglqfpvgrvhrllrkgnyservgagapvylaavle
yltaeilelagnaardnkktriiprhlqlairndeelnkllgrvtiaqggvlpniqavll
pkkteshhkakgk

    Sequence, based on observed residues (ATOM records):
    >3an2G (G:)
ktrssraglqfpvgrvhrllrkgnyservgagapvylaavleyltaeilelagnaardnk
ktriiprhlqlairndeelnkllgrvtiaqggvlpniqav

  • Chain 'H':
    Sequence, based on SEQRES records:
    >3an2H (H:)
gshmpepaksapapkkgskkavtkaqkkdgkkrkrsrkesysiyvykvlkqvhpdtgiss
kamgimnsfvndiferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtk
avtkytsak

    Sequence, based on observed residues (ATOM records):
    >3an2H (H:)
esysiyvykvlkqvhpdtgisskamgimnsfvndiferiageasrlahynkrstitsrei
qtavrlllpgelakhavsegtkavtkytsa

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    No sequence available.