PDB entry 3an0

View 3an0 on RCSB PDB site
Description: Crystal structure of non-phosphorylated MAP2K6 as a putative auto inhibition state
Class: transferase/transferase inhibitor
Keywords: auto inhibition state, activation helix, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2010-08-27, released 2011-09-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-02-29, with a file datestamp of 2012-02-24.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.269
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dual specificity mitogen-activated protein kinase kinase 6
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3an0a_
  • Heterogens: ANK, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3an0A (A:)
msqskgkkrnpglkipkeafeqpqtsstpprdldskacisignqnfevkaddlepimelg
rgaygvvekmrhvpsgqimavkriratvnsqeqkrllmdldismrtvdcpftvtfygalf
regdvwicmelmdtsldkfykqvidkgqtipedilgkiavsivkalehlhsklsvihrdv
kpsnvlinalgqvkmcdfgisgylvdsvaktidagckpymaperinpelnqkgysvksdi
wslgitmielailrfpydswgtpfqqlkqvveepspqlpadkfsaefvdftsqclkknsk
erptypelmqhpfftlheskgtdvasfvklilgdhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3an0A (A:)
qnfevkaddlepimelgrgaygvvekmrhvpsgqimavkriratvnsqeqkrllmdldis
mrtvdcpftvtfygalfregdvwicmelmdtsldkfykqvidkgqtipedilgkiavsiv
kalehlhsklsvihrdvkpsnvlinalgqvkmcdfgisgylvdsvaktidagckpymape
rinpelnqkgysvksdiwslgitmielailrfpydswgtpfqqlkqvveepspqlpadkf
saefvdftsqclkknskerptypelmqhpfftlheskgtdvasfvklilgd