PDB entry 3alx

View 3alx on RCSB PDB site
Description: crystal structure of the measles virus hemagglutinin bound to its cellular receptor slam (mv-h(l482r)-slam(n102h/r108y) fusion)
Deposited on 2010-08-09, released 2011-01-12
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 3.15 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hemagglutinin,LINKER,CDw150
    Species: Saguinus oedipus [TaxId:9490]
    Gene: CDw150
    Database cross-references and differences (RAF-indexed):
    • Uniprot E2RZS2
      • engineered mutation (301)
    • PDB 3ALX
    • Uniprot Q9GJT3
      • engineered mutation (511)
      • engineered mutation (517)
  • Chain 'B':
    Compound: Hemagglutinin,LINKER,CDw150
    Species: Saguinus oedipus [TaxId:9490]
    Gene: CDw150
    Database cross-references and differences (RAF-indexed):
    • Uniprot E2RZS2
      • engineered mutation (301)
    • PDB 3ALX
    • Uniprot Q9GJT3 (Start-549)
      • engineered mutation (511)
      • engineered mutation (517)
  • Chain 'C':
    Compound: Hemagglutinin,LINKER,CDw150
    Species: Saguinus oedipus [TaxId:9490]
    Gene: CDw150
    Database cross-references and differences (RAF-indexed):
    • Uniprot E2RZS2 (Start-426)
      • engineered mutation (301)
    • PDB 3ALX
    • Uniprot Q9GJT3 (439-End)
      • engineered mutation (511)
      • engineered mutation (517)
  • Chain 'D':
    Compound: Hemagglutinin,LINKER,CDw150
    Species: Saguinus oedipus [TaxId:9490]
    Gene: CDw150
    Database cross-references and differences (RAF-indexed):
    • Uniprot E2RZS2
      • engineered mutation (301)
    • PDB 3ALX
    • Uniprot Q9GJT3 (439-End)
      • engineered mutation (511)
      • engineered mutation (517)
  • Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3alxA (A:)
etgskgncsgpttirgqfsnmslslldlylgrgynvssivtmtsqgmyggtylvekpnls
skrselsqlsmyrvfevgvirnpglgapvfhmtnyleqpvsndlsncmvalgelklaalc
hgedsitipyqgsgkgvsfqlvklgvwksptdmqswvplstddpvidrlylsshrgviad
nqakwavpttrtddklrmetcfqqackgkiqalcenpewaplkdnripsygvlsvdlslt
velkikiasgfgplithgsgmdlyksnhnnvywltippmknlalgvintlewiprfkvsp
yrftvpikeaggdchaptylpaevdgdvklssnlvilpgqdlqyvlatydtsrvehavvy
yvyspsrsfsyfypfrlpikgvpielqvecftwdqklwcrhfcvladsesgghithsgmv
gmgvsctgggsgggsgggsmncpkivqqlgsdvllpltherintsmnksihivvtmaksl
ensvenkivsldpseagpprylkdryrfylehlslaiyestkkdegwyfmtleknisvqr
fclhlklyeqgtkhhhhhh

    Sequence, based on observed residues (ATOM records):
    >3alxA (A:)
csgpttirgqfsnmslslldlylgrgynvssivtmtsqgmyggtylvekpsmyrvfevgv
irnpglgapvfhmtnyleqpvsndlsncmvalgelklaalchgedsitipyqgsgkgvsf
qlvklgvwksptdmqswvplstddpvidrlylsshrgviadnqakwavpttrtddklrme
tcfqqackgkiqalcenpewaplkdnripsygvlsvdlsltvelkikiasgfgplithgs
gmdlyksnhnnvywltippmknlalgvintlewiprfkvspyrftvpikeaggdchapty
lpaevdgdvklssnlvilpgqdlqyvlatydtsrvehavvyyvyspsrsfsyfypfrlpi
kgvpielqvecftwdqklwcrhfcvladsesgghithsgmvgmgvsccpkivqqlgsdvl
lpltherintsmnksihivvtmakslensvenkivsldpseagpprylkdryrfylehls
laiyestkkdegwyfmtleknisvqrfclhlklye

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3alxB (B:)
etgskgncsgpttirgqfsnmslslldlylgrgynvssivtmtsqgmyggtylvekpnls
skrselsqlsmyrvfevgvirnpglgapvfhmtnyleqpvsndlsncmvalgelklaalc
hgedsitipyqgsgkgvsfqlvklgvwksptdmqswvplstddpvidrlylsshrgviad
nqakwavpttrtddklrmetcfqqackgkiqalcenpewaplkdnripsygvlsvdlslt
velkikiasgfgplithgsgmdlyksnhnnvywltippmknlalgvintlewiprfkvsp
yrftvpikeaggdchaptylpaevdgdvklssnlvilpgqdlqyvlatydtsrvehavvy
yvyspsrsfsyfypfrlpikgvpielqvecftwdqklwcrhfcvladsesgghithsgmv
gmgvsctgggsgggsgggsmncpkivqqlgsdvllpltherintsmnksihivvtmaksl
ensvenkivsldpseagpprylkdryrfylehlslaiyestkkdegwyfmtleknisvqr
fclhlklyeqgtkhhhhhh

    Sequence, based on observed residues (ATOM records):
    >3alxB (B:)
csgpttirgqfsnmslslldlylgrgynvssivtmtsqgmyggtylvekpnlsskrlsql
smyrvfevgvirnpglgapvfhmtnyleqpvsndlsncmvalgelklaalchgedsitip
yqgsgkgvsfqlvklgvwksptdmqswvplstddpvidrlylsshrgviadnqakwavpt
trtddklrmetcfqqackgkiqalcenpewaplkdnripsygvlsvdlsltvelkikias
gfgplithgsgmdlyksnhnnvywltippmknlalgvintlewiprfkvspyrftvpike
aggdchaptylpaevdgdvklssnlvilpgqdlqyvlatydtsrvehavvyyvyspsrsf
syfypfrlpikgvpielqvecftwdqklwcrhfcvladsesgghithsgmvgmgvsccpk
ivqqlgsdvllpltherintsmnksihivvtmakslensvenkivsldpseagpprylkd
ryrfylehlslaiyestkkdegwyfmtleknisvqrfclhlklyeq

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3alxC (C:)
etgskgncsgpttirgqfsnmslslldlylgrgynvssivtmtsqgmyggtylvekpnls
skrselsqlsmyrvfevgvirnpglgapvfhmtnyleqpvsndlsncmvalgelklaalc
hgedsitipyqgsgkgvsfqlvklgvwksptdmqswvplstddpvidrlylsshrgviad
nqakwavpttrtddklrmetcfqqackgkiqalcenpewaplkdnripsygvlsvdlslt
velkikiasgfgplithgsgmdlyksnhnnvywltippmknlalgvintlewiprfkvsp
yrftvpikeaggdchaptylpaevdgdvklssnlvilpgqdlqyvlatydtsrvehavvy
yvyspsrsfsyfypfrlpikgvpielqvecftwdqklwcrhfcvladsesgghithsgmv
gmgvsctgggsgggsgggsmncpkivqqlgsdvllpltherintsmnksihivvtmaksl
ensvenkivsldpseagpprylkdryrfylehlslaiyestkkdegwyfmtleknisvqr
fclhlklyeqgtkhhhhhh

    Sequence, based on observed residues (ATOM records):
    >3alxC (C:)
csgpttirgqfsnmslslldlylgrgynvssivtmtsqgmyggtylvekpnlqlsmyrvf
evgvirnpglgapvfhmtnyleqpvsndlsncmvalgelklaalchgedsitipysgkgv
sfqlvklgvwksptdmqswvplstddpvidrlylsshrgviadnqakwavpttrtddklr
metcfqqackgkiqalcenpewaplkdnripsygvlsvdlsltvelkikiasgfgplith
gsgmdlyksnhnnvywltippmknlalgvintlewiprfkvspyrftvpikeaggdchap
tylpaevdgdvklssnlvilpgqdlqyvlatydtsrvehavvyyvyspsrsfsyfypfrl
pikgvpielqvecftwdqklwcrhfcvladsesgghithsgmvgmgvsctmncpkivqql
gsdvllpltherksihivvtmakslensvenkivsldpseagpprylkdryrfylehlsl
aiyestkkdegwyfmtleknisvqrfclhlklye

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3alxD (D:)
etgskgncsgpttirgqfsnmslslldlylgrgynvssivtmtsqgmyggtylvekpnls
skrselsqlsmyrvfevgvirnpglgapvfhmtnyleqpvsndlsncmvalgelklaalc
hgedsitipyqgsgkgvsfqlvklgvwksptdmqswvplstddpvidrlylsshrgviad
nqakwavpttrtddklrmetcfqqackgkiqalcenpewaplkdnripsygvlsvdlslt
velkikiasgfgplithgsgmdlyksnhnnvywltippmknlalgvintlewiprfkvsp
yrftvpikeaggdchaptylpaevdgdvklssnlvilpgqdlqyvlatydtsrvehavvy
yvyspsrsfsyfypfrlpikgvpielqvecftwdqklwcrhfcvladsesgghithsgmv
gmgvsctgggsgggsgggsmncpkivqqlgsdvllpltherintsmnksihivvtmaksl
ensvenkivsldpseagpprylkdryrfylehlslaiyestkkdegwyfmtleknisvqr
fclhlklyeqgtkhhhhhh

    Sequence, based on observed residues (ATOM records):
    >3alxD (D:)
pttirgqfsnmslslldlylgrgynvssivtmtsqgmyggtylvekpqlsmyrvfevgvi
rnpglgapvfhmtnyleqpvsndlsncmvalgelklaalchgedsitipysgkgvsfqlv
klgvwksptdmqswvplstddpvidrlylsshrgviadnqakwavpttrtddklrmetcf
qqackgkiqalcenpewaplkdnripsygvlsvdlsltvelkikiasgfgplithgsgmd
lyksnhnnvywltippmknlalgvintlewiprfkvspyrftvpikeaggdchaptylpa
evdgdvklssnlvilpgqdlqyvlatydtsrvehavvyyvyspsrsfsyfypfrlpikgv
pielqvecftwdqklwcrhfcvladghithsgmvgmgvscmncpkivqqlgsdvllplth
enksihivvtmakslensvenkivsldpseagpprylkdryrfylehlslaiyestkkde
gwyfmtleknisvqrfclhlklye