PDB entry 3alo

View 3alo on RCSB PDB site
Description: crystal structure of human non-phosphorylated mkk4 kinase domain ternary complex with amp-pnp and p38 peptide
Deposited on 2010-08-04, released 2010-10-27
The last revision was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dual specificity mitogen-activated protein kinase kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: JNKK1, MAP2K4, MEK4, MKK4, PRKMK4, SERK1
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: p38 peptide
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3ALO (0-7)
  • Heterogens: MG, ANP, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3aloA (A:)
msiessgklkispeqhwdftaedlkdlgeigrgaygsvnkmvhkpsgqimavkrirstvd
ekeqkqllmdldvvmrssdcpyivqfygalfregdcwicmelmstsfdkfykyvysvldd
vipeeilgkitlatvkalnhlkenlkiihrdikpsnilldrsgniklcdfgisgqlvdsi
aktrdagcrpymaperidpsasrqgydvrsdvwslgitlyelatgrfpypkwnsvfdqlt
qvvkgdppqlsnseerefspsfinfvnlcltkdeskrpkykellkhpfilmyeeraveva
cyvckildqmpatpsspmyvdhhhhhh

    Sequence, based on observed residues (ATOM records):
    >3aloA (A:)
wdftaedlkdlgeigrgaygsvnkmvhkpsgqimavkrirstvdekeqkqllmdldvvmr
ssdcpyivqfygalfregdcwicmelmstsfdkfykyvysvlddvipeeilgkitlatvk
alnhlkenlkiihrdikpsnilldrsgniklcdfgisgqlvdsiaktrdagcrpymaper
idpydvrsdvwslgitlyelatgrfpypkwnsvfdqltqvvkgdppqlsnseerefspsf
infvnlcltkdeskrpkykellkhpfilmyeeravevacyvckildqmp

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records:
    >3aloE (E:)
ddemtgya