PDB entry 3agm
View 3agm on RCSB PDB site
Description: Complex of PKA with the bisubstrate protein kinase inhibitor ARC-670
Class: transferase/transferase inhibitor
Keywords: PKA, protein kinase A, bisubstrate, bisubstrate inhibitor, ARC-670, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
Deposited on
2010-04-02, released
2010-09-01
The last revision prior to the SCOPe 2.01 freeze date was dated
2011-10-05, with a file datestamp of
2011-09-30.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.225
AEROSPACI score: 0.42
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: cAMP-dependent protein kinase catalytic subunit alpha
Species: Homo sapiens [TaxId:9606]
Gene: Pkaca, Prkaca
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d3agma_ - Chain 'B':
Compound: n~2~-{8-oxo-8-[4-(9h-purin-6-yl)piperazin-1-yl]octanoyl}-d-arginyl-d-arginyl-d-arginyl-d-arginyl-d-arginyl-d-argininamide
Database cross-references and differences (RAF-indexed):
- Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3agmA (A:)
mgnaaaakkgseqesvkeflakakedflkkwespaqntahldqferiktlgtgsfgrvml
vkhketgnhyamkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymv
meyvpggemfshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgy
iqvtdfgfakrvkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppff
adqpiqiyekivsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfat
tdwiaiyqrkveapfipkfkgpgdtsnfddyeeeeirvsinekcgkefsef
Sequence, based on observed residues (ATOM records): (download)
>3agmA (A:)
qesvkeflakakedflkkwespaqntahldqferiktlgtgsfgrvmlvkhketgnhyam
kildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvpggemfsh
lrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfakrv
kgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekiv
sgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkve
apfipkfkgpgdtsnfddyeeeeirvsinekcgkefsef
- Chain 'B':
No sequence available.