PDB entry 3afr

View 3afr on RCSB PDB site
Description: Crystal Structure of VDR-LBD/22S-Butyl-1a,24R-dihydroxyvitamin D3 complex
Class: TRANSCRIPTION/Transcription regulator
Keywords: Vitamin D Receptor, nuclear receptor, agonist, antagonist, vitamin D derivative, DNA-binding, Nucleus, Receptor, Transcription, Transcription regulation, TRANSCRIPTION-Transcription regulator complex
Deposited on 2010-03-10, released 2010-03-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Vitamin D3 receptor
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Vdr, Nr1i1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3afra_
  • Chain 'C':
    Compound: 13-meric peptide from Mediator of RNA polymerase II transcription subunit 1
    Species: Xenopus tropicalis, synthetic [TaxId:8364]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ICJ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3afrA (A:)
gshmgspnsplkdslrpklseeqqhiiailldahhktydptyadfrdfrppvrmdgstgs
vtldlsplsmlphladlvsysiqkvigfakmipgfrdltsddqivllkssaievimlrsn
qsftmddmswdcgsqdykydvtdvskaghtlelieplikfqvglkklnlheeehvllmai
civspdrpgvqdaklveaiqdrlsntlqtyircrhpppgshqlyakmiqkladlrslnee
hskqyrslsfqpensmkltplvlevfgneis

    Sequence, based on observed residues (ATOM records): (download) 
    >3afrA (A:)
klseeqqhiiailldahhktydptyadfrdfrppvrmsplsmlphladlvsysiqkvigf
akmipgfrdltsddqivllkssaievimlrsnqsftmddmswdcgsqdykydvtdvskag
htlelieplikfqvglkklnlheeehvllmaicivspdrpgvqdaklveaiqdrlsntlq
tyircrhpppgshqlyakmiqkladlrslneehskqyrslsfqpensmkltplvlevfgn

  • Chain 'C':
    No sequence available.