PDB entry 3afn

View 3afn on RCSB PDB site
Description: Crystal structure of aldose reductase A1-R complexed with NADP
Class: Oxidoreductase
Keywords: ALPHA/BETA/ALPHA, ROSSMANN-FOLD, Oxidoreductase
Deposited on 2010-03-10, released 2010-08-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-08-25, with a file datestamp of 2010-08-20.
Experiment type: XRAY
Resolution: 1.63 Å
R-factor: 0.174
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: carbonyl reductase
    Species: Sphingomonas sp. [TaxId:90322]
    Gene: a1-R
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3afna_
  • Chain 'B':
    Compound: carbonyl reductase
    Species: Sphingomonas sp. [TaxId:90322]
    Gene: a1-R
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3afnb_
  • Chain 'C':
    Compound: carbonyl reductase
    Species: Sphingomonas sp. [TaxId:90322]
    Gene: a1-R
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3afnc_
  • Chain 'D':
    Compound: carbonyl reductase
    Species: Sphingomonas sp. [TaxId:90322]
    Gene: a1-R
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3afnd_
  • Heterogens: NAP, TBU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3afnA (A:)
mfpdlkgkrvlitgssqgiglatarlfaragakvglhgrkapanidetiasmradggdaa
ffaadlatseacqqlvdefvakfggidvlinnagglvgrkplpeiddtfydavmdanirs
vvmttkfalphlaaaakasgqtsavistgsiaghtgggpgaglygaakaflhnvhknwvd
fhtkdgvrfnivspgtvdtafhadktqdvrdrisngipmgrfgtaeemapaflffashla
sgyitgqvldinggqykh

    Sequence, based on observed residues (ATOM records): (download) 
    >3afnA (A:)
fpdlkgkrvlitgssqgiglatarlfaragakvglhgrkapanidetiasmradggdaaf
faadlatseacqqlvdefvakfggidvlinnagglvgrkplpeiddtfydavmdanirsv
vmttkfalphlaaaakasgqtsavistgsiaghtgggpgaglygaakaflhnvhknwvdf
htkdgvrfnivspgtvdtafhadktqdvrdrisngipmgrfgtaeemapaflffashlas
gyitgqvldinggqykh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3afnB (B:)
mfpdlkgkrvlitgssqgiglatarlfaragakvglhgrkapanidetiasmradggdaa
ffaadlatseacqqlvdefvakfggidvlinnagglvgrkplpeiddtfydavmdanirs
vvmttkfalphlaaaakasgqtsavistgsiaghtgggpgaglygaakaflhnvhknwvd
fhtkdgvrfnivspgtvdtafhadktqdvrdrisngipmgrfgtaeemapaflffashla
sgyitgqvldinggqykh

    Sequence, based on observed residues (ATOM records): (download) 
    >3afnB (B:)
fpdlkgkrvlitgssqgiglatarlfaragakvglhgrkapanidetiasmradggdaaf
faadlatseacqqlvdefvakfggidvlinnagglvgrkplpeiddtfydavmdanirsv
vmttkfalphlaaaakasgqtsavistgsiaghtgggpgaglygaakaflhnvhknwvdf
htkdgvrfnivspgtvdtafhadktqdvrdrisngipmgrfgtaeemapaflffashlas
gyitgqvldinggqykh

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3afnC (C:)
mfpdlkgkrvlitgssqgiglatarlfaragakvglhgrkapanidetiasmradggdaa
ffaadlatseacqqlvdefvakfggidvlinnagglvgrkplpeiddtfydavmdanirs
vvmttkfalphlaaaakasgqtsavistgsiaghtgggpgaglygaakaflhnvhknwvd
fhtkdgvrfnivspgtvdtafhadktqdvrdrisngipmgrfgtaeemapaflffashla
sgyitgqvldinggqykh

    Sequence, based on observed residues (ATOM records): (download) 
    >3afnC (C:)
fpdlkgkrvlitgssqgiglatarlfaragakvglhgrkapanidetiasmradggdaaf
faadlatseacqqlvdefvakfggidvlinnagglvgrkplpeiddtfydavmdanirsv
vmttkfalphlaaaakasgqtsavistgsiaghtgggpgaglygaakaflhnvhknwvdf
htkdgvrfnivspgtvdtafhadktqdvrdrisngipmgrfgtaeemapaflffashlas
gyitgqvldinggqykh

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3afnD (D:)
mfpdlkgkrvlitgssqgiglatarlfaragakvglhgrkapanidetiasmradggdaa
ffaadlatseacqqlvdefvakfggidvlinnagglvgrkplpeiddtfydavmdanirs
vvmttkfalphlaaaakasgqtsavistgsiaghtgggpgaglygaakaflhnvhknwvd
fhtkdgvrfnivspgtvdtafhadktqdvrdrisngipmgrfgtaeemapaflffashla
sgyitgqvldinggqykh

    Sequence, based on observed residues (ATOM records): (download) 
    >3afnD (D:)
fpdlkgkrvlitgssqgiglatarlfaragakvglhgrkapanidetiasmradggdaaf
faadlatseacqqlvdefvakfggidvlinnagglvgrkplpeiddtfydavmdanirsv
vmttkfalphlaaaakasgqtsavistgsiaghtgggpgaglygaakaflhnvhknwvdf
htkdgvrfnivspgtvdtafhadktqdvrdrisngipmgrfgtaeemapaflffashlas
gyitgqvldinggqykh