PDB entry 3aem

View 3aem on RCSB PDB site
Description: Reaction intermediate structure of Entamoeba histolytica methionine gamma-lyase 1 containing Michaelis complex and methionine imine-pyridoxamine-5'-phosphate
Class: lyase
Keywords: gamma-lyase, L-methionine, entamoeba histolytica, lyase
Deposited on 2010-02-10, released 2011-02-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: methionine gamma-lyase
    Species: Entamoeba histolytica [TaxId:5759]
    Gene: metG
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q86D28
      • see remark 999 (307)
    Domains in SCOPe 2.08: d3aema_
  • Chain 'B':
    Compound: methionine gamma-lyase
    Species: Entamoeba histolytica [TaxId:5759]
    Gene: metG
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q86D28
      • see remark 999 (307)
    Domains in SCOPe 2.08: d3aemb_
  • Chain 'C':
    Compound: methionine gamma-lyase
    Species: Entamoeba histolytica [TaxId:5759]
    Gene: metG
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q86D28 (Start-388)
      • see remark 999 (307)
    Domains in SCOPe 2.08: d3aemc_
  • Chain 'D':
    Compound: methionine gamma-lyase
    Species: Entamoeba histolytica [TaxId:5759]
    Gene: metG
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q86D28
      • see remark 999 (307)
    Domains in SCOPe 2.08: d3aemd_
  • Heterogens: 2LM, SO4, GOL, MET, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3aemA (A:)
mtaqditttllhpkgdhvlhshaypifqtstfcfdstqqgadlfmgkgeghiysrlgnpt
veqfeemvcsiegaagsaafgsgmgaissstlaflqkgdhliagdtlygctvslfthwlp
rfgievdlidtsdvekvkaawkpntkmvylespanptckvsdikgiavvchergarlvvd
atftspcflkplelgadialhsvskyinghgdviggvssaktaediatikfyrkdagslm
apmdaflcargmktlpirmqihmenglkvakfleqhekivkvnhpglesfpghdiakkqm
tgygstflfemksfeaakklmehlkvctlavslgcvdtliehpasmthaavpenimrkqg
itpelvrisvgienvddiiadlkqalelw

    Sequence, based on observed residues (ATOM records): (download) 
    >3aemA (A:)
aqditttllhpkgdhvlhshaypifqtstfcfdstqqgadlfmgkgeghiysrlgnptve
qfeemvcsiegaagsaafgsgmgaissstlaflqkgdhliagdtlygctvslfthwlprf
gievdlidtsdvekvkaawkpntkmvylespanptckvsdikgiavvchergarlvvdat
ftspcflkplelgadialhsvskyinghgdviggvssaktaediatikfyrkdagslmap
mdaflcargmktlpirmqihmenglkvakfleqhekivkvnhpglesfpghdiakkqmtg
ygstflfemksfeaakklmehlkvctlavslgcvdtliehpasmthaavpenimrkqgit
pelvrisvgienvddiiadlkqalelw

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3aemB (B:)
mtaqditttllhpkgdhvlhshaypifqtstfcfdstqqgadlfmgkgeghiysrlgnpt
veqfeemvcsiegaagsaafgsgmgaissstlaflqkgdhliagdtlygctvslfthwlp
rfgievdlidtsdvekvkaawkpntkmvylespanptckvsdikgiavvchergarlvvd
atftspcflkplelgadialhsvskyinghgdviggvssaktaediatikfyrkdagslm
apmdaflcargmktlpirmqihmenglkvakfleqhekivkvnhpglesfpghdiakkqm
tgygstflfemksfeaakklmehlkvctlavslgcvdtliehpasmthaavpenimrkqg
itpelvrisvgienvddiiadlkqalelw

    Sequence, based on observed residues (ATOM records): (download) 
    >3aemB (B:)
aqditttllhpkgdhvlhshaypifqtstfcfdstqqgadlfmgkgeghiysrlgnptve
qfeemvcsiegaagsaafgsgmgaissstlaflqkgdhliagdtlygctvslfthwlprf
gievdlidtsdvekvkaawkpntkmvylespanptckvsdikgiavvchergarlvvdat
ftspcflkplelgadialhsvskyinghgdviggvssaktaediatikfyrkdagslmap
mdaflcargmktlpirmqihmenglkvakfleqhekivkvnhpglesfpghdiakkqmtg
ygstflfemksfeaakklmehlkvctlavslgcvdtliehpasmthaavpenimrkqgit
pelvrisvgienvddiiadlkqalel

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3aemC (C:)
mtaqditttllhpkgdhvlhshaypifqtstfcfdstqqgadlfmgkgeghiysrlgnpt
veqfeemvcsiegaagsaafgsgmgaissstlaflqkgdhliagdtlygctvslfthwlp
rfgievdlidtsdvekvkaawkpntkmvylespanptckvsdikgiavvchergarlvvd
atftspcflkplelgadialhsvskyinghgdviggvssaktaediatikfyrkdagslm
apmdaflcargmktlpirmqihmenglkvakfleqhekivkvnhpglesfpghdiakkqm
tgygstflfemksfeaakklmehlkvctlavslgcvdtliehpasmthaavpenimrkqg
itpelvrisvgienvddiiadlkqalelw

    Sequence, based on observed residues (ATOM records): (download) 
    >3aemC (C:)
aqditttllhpkgdhvlhshaypifqtstfcfdstqqgadlfmgkgeghiysrlgnptve
qfeemvcsiegaagsaafgsgmgaissstlaflqkgdhliagdtlygctvslfthwlprf
gievdlidtsdvekvkaawkpntkmvylespanptckvsdikgiavvchergarlvvdat
ftspcflkplelgadialhsvskyinghgdviggvssaktaediatikfyrkdagslmap
mdaflcargmktlpirmqihmenglkvakfleqhekivkvnhpglesfpghdiakkqmtg
ygstflfemksfeaakklmehlkvctlavslgcvdtliehpasmthaavpenimrkqgit
pelvrisvgienvddiiadlkqalelw

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3aemD (D:)
mtaqditttllhpkgdhvlhshaypifqtstfcfdstqqgadlfmgkgeghiysrlgnpt
veqfeemvcsiegaagsaafgsgmgaissstlaflqkgdhliagdtlygctvslfthwlp
rfgievdlidtsdvekvkaawkpntkmvylespanptckvsdikgiavvchergarlvvd
atftspcflkplelgadialhsvskyinghgdviggvssaktaediatikfyrkdagslm
apmdaflcargmktlpirmqihmenglkvakfleqhekivkvnhpglesfpghdiakkqm
tgygstflfemksfeaakklmehlkvctlavslgcvdtliehpasmthaavpenimrkqg
itpelvrisvgienvddiiadlkqalelw

    Sequence, based on observed residues (ATOM records): (download) 
    >3aemD (D:)
ditttllhpkgdhvlhshaypifqtstfcfdstqqgadlfmgkgeghiysrlgnptveqf
eemvcsiegaagsaafgsgmgaissstlaflqkgdhliagdtlygctvslfthwlprfgi
evdlidtsdvekvkaawkpntkmvylespanptckvsdikgiavvchergarlvvdatft
spcflkplelgadialhsvskyinghgdviggvssaktaediatikfyrkdagslmapmd
aflcargmktlpirmqihmenglkvakfleqhekivkvnhpglesfpghdiakkqmtgyg
stflfemksfeaakklmehlkvctlavslgcvdtliehpasmthaavpenimrkqgitpe
lvrisvgienvddiiadlkqalel