PDB entry 3aeb

View 3aeb on RCSB PDB site
Description: Crystal structure of porcine heart mitochondrial complex II bound with N-(3-Phenoxy-phenyl)-2-trifluoromethyl-benzamide
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: respiratory complex II, inhibitors, Electron transport, Iron, Iron-sulfur, Metal-binding, Mitochondrion, Mitochondrion inner membrane, Oxidoreductase, Transit peptide, Transport, Tricarboxylic acid cycle, Heme, Transmembrane, FAD-binding protein, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Deposited on 2010-02-04, released 2011-02-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3aebb1, d3aebb2
  • Chain 'C':
    Compound: Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3aebd_
  • Heterogens: FAD, MLI, FES, F3S, SF4, HEM, F7A, EPH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3aebB (B:)
aqtaaataprikkfaiyrwdpdktgdkphmqtyeidlnncgpmvldalikikneidstlt
frrscregicgscamninggntlactrridtnldkvskiyplphmyvikdlvpdlsnfya
qyksiepylkkkdesqegkqqylqsieerekldglyecilcaccstscpsywwngdkylg
pavlmqayrwmidsrddfteerlaklqdpfslyrchtimnctgtcpkglnpgkaiaeikk
mmatykekkasa

    Sequence, based on observed residues (ATOM records): (download) 
    >3aebB (B:)
prikkfaiyrwdpdktgdkphmqtyeidlnncgpmvldalikikneidstltfrrscreg
icgscamninggntlactrridtnldkvskiyplphmyvikdlvpdlsnfyaqyksiepy
lkkkdesqegkqqylqsieerekldglyecilcaccstscpsywwngdkylgpavlmqay
rwmidsrddfteerlaklqdpfslyrchtimnctgtcpkglnpgkaiaeikkmmatyke

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3aebD (D:)
asskaaslhwtgervvsvlllgllpaaylnpcsamdyslaaaltlhghwgigqvvtdyvr
gdalqkaakagllalsaftfaglcyfnyhdvgickavamlwkl

    Sequence, based on observed residues (ATOM records): (download) 
    >3aebD (D:)
sskaaslhwtgervvsvlllgllpaaylnpcsamdyslaaaltlhghwgigqvvtdyvrg
dalqkaakagllalsaftfaglcyfnyhdvgickavamlwkl