PDB entry 3ae0

View 3ae0 on RCSB PDB site
Description: crystal structure of the c(30) carotenoid dehydrosqualene synthase from staphylococcus aureus complexed with geranylgeranyl thiopyrophosphate
Deposited on 2010-01-31, released 2010-11-24
The last revision was dated 2021-11-10, with a file datestamp of 2021-11-05.
Experiment type: XRAY
Resolution: 2.37 Å
R-factor: 0.222
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dehydrosqualene synthase
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: CrtM
    Database cross-references and differences (RAF-indexed):
    • Uniprot A9JQL9 (6-292)
      • expression tag (0-5)
      • engineered mutation (31)
  • Chain 'B':
    Compound: Dehydrosqualene synthase
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: CrtM
    Database cross-references and differences (RAF-indexed):
    • Uniprot A9JQL9 (6-292)
      • expression tag (0-5)
      • engineered mutation (31)
  • Heterogens: GGS, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3ae0A (A:)
aaaaaamtmmdmnfkychkimkkhsksfsyaadllpedqrkavwaiyavcrkiddsidvy
gdiqflnqikediqsiekypyeyhhfqsdrrimmalqhvaqhkniafqsfynlidtvykd
qhftmfetdaelfgycygvagtvgevltpilsdhethqtydvarrlgeslqlinilrdvg
edfeneriyfskqrlkqyevdiaevyqngvnnhyidlweyyaaiaekdfrdvmdqikvfs
ieaqpiielaariyieildevrqanytlhervfvekrkkaklfheinskyhri

    Sequence, based on observed residues (ATOM records):
    >3ae0A (A:)
mtmmdmnfkychkimkkhsksfsyaadllpedqrkavwaiyavcrkiddsidvygdiqfl
nqikediqsiekypyeyhhfqsdrrimmalqhvaqhkniafqsfynlidtvykdqhftmf
etdaelfgycygvagtvgevltpilsdhethqtydvarrlgeslqlinilrdvgedfene
riyfskqrlkqyevdiaevyqngvnnhyidlweyyaaiaekdfrdvmdqikvfsieaqpi
ielaariyieildevrqanytlhervfvekrkkaklfheinsky

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3ae0B (B:)
aaaaaamtmmdmnfkychkimkkhsksfsyaadllpedqrkavwaiyavcrkiddsidvy
gdiqflnqikediqsiekypyeyhhfqsdrrimmalqhvaqhkniafqsfynlidtvykd
qhftmfetdaelfgycygvagtvgevltpilsdhethqtydvarrlgeslqlinilrdvg
edfeneriyfskqrlkqyevdiaevyqngvnnhyidlweyyaaiaekdfrdvmdqikvfs
ieaqpiielaariyieildevrqanytlhervfvekrkkaklfheinskyhri

    Sequence, based on observed residues (ATOM records):
    >3ae0B (B:)
mtmmdmnfkychkimkkhsksfsyaadllpedqrkavwaiyavcrkiddsidvygdiqfl
nqikediqsiekypyeyhhfqsdrrimmalqhvaqhkniafqsfynlidtvykdqhftmf
etdaelfgycygvagtvgevltpilsdhethqtydvarrlgeslqlinilrdvgedfene
riyfskqrlkqyevdiaevyqngvnnhyidlweyyaaiaekdfrdvmdqikvfsieaqpi
ielaariyieildevrqanytlhervfvekrkkaklfheinsky