PDB entry 3ab4

View 3ab4 on RCSB PDB site
Description: Crystal structure of feedback inhibition resistant mutant of aspartate kinase from Corynebacterium glutamicum in complex with lysine and threonine
Deposited on 2009-11-30, released 2010-06-23
The last revision was dated 2010-09-01, with a file datestamp of 2010-08-27.
Experiment type: XRAY
Resolution: 2.47 Å
R-factor: 0.226
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aspartokinase
    Species: Corynebacterium glutamicum [TaxId:1718]
    Gene: lysC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26512
      • see remark 999 (300)
  • Chain 'B':
    Compound: aspartokinase
    Species: Corynebacterium glutamicum [TaxId:1718]
    Gene: lysC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26512
      • see remark 999 (51)
  • Chain 'C':
    Compound: aspartokinase
    Species: Corynebacterium glutamicum [TaxId:1718]
    Gene: lysC
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: aspartokinase
    Species: Corynebacterium glutamicum [TaxId:1718]
    Gene: lysC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26512
      • see remark 999 (51)
  • Chain 'E':
    Compound: aspartokinase
    Species: Corynebacterium glutamicum [TaxId:1718]
    Gene: lysC
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: aspartokinase
    Species: Corynebacterium glutamicum [TaxId:1718]
    Gene: lysC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26512
      • see remark 999 (51)
  • Chain 'G':
    Compound: aspartokinase
    Species: Corynebacterium glutamicum [TaxId:1718]
    Gene: lysC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26512
      • see remark 999 (300)
  • Chain 'H':
    Compound: aspartokinase
    Species: Corynebacterium glutamicum [TaxId:1718]
    Gene: lysC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26512
      • see remark 999 (51)
  • Chain 'I':
    Compound: aspartokinase
    Species: Corynebacterium glutamicum [TaxId:1718]
    Gene: lysC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26512
      • see remark 999 (300)
  • Chain 'J':
    Compound: aspartokinase
    Species: Corynebacterium glutamicum [TaxId:1718]
    Gene: lysC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26512
      • see remark 999 (51)
  • Chain 'K':
    Compound: aspartokinase
    Species: Corynebacterium glutamicum [TaxId:1718]
    Gene: lysC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26512
      • see remark 999 (300)
  • Chain 'L':
    Compound: aspartokinase
    Species: Corynebacterium glutamicum [TaxId:1718]
    Gene: lysC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26512 (1-End)
      • see remark 999 (51)
  • Chain 'M':
    Compound: aspartokinase
    Species: Corynebacterium glutamicum [TaxId:1718]
    Gene: lysC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26512
      • see remark 999 (300)
  • Chain 'N':
    Compound: aspartokinase
    Species: Corynebacterium glutamicum [TaxId:1718]
    Gene: lysC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26512
      • see remark 999 (51)
  • Chain 'O':
    Compound: aspartokinase
    Species: Corynebacterium glutamicum [TaxId:1718]
    Gene: lysC
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: aspartokinase
    Species: Corynebacterium glutamicum [TaxId:1718]
    Gene: lysC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26512
      • see remark 999 (51)
  • Heterogens: THR, LYS, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3ab4A (A:)
malvvqkyggsslesaerirnvaerivatkkagndvvvvcsamgdttdellelaaavnpv
pparemdmlltagerisnalvamaieslgaeaqsftgsqagvltterhgnarivdvtpgr
vrealdegkicivagfqgvnketrdvttlgrggsdttavalaaalnadvceiysdvdgvy
tadprivpnaqkleklsfeemlelaavgskilvlrsveyarafnvplrvrssysndpgtl
iagsmedipveeavltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnv
fsvedgttditftcprsdgrrameilkklqvqgnwtnvlyddqvgkvslvgagmkshpgv
taefmealrdvnvnielistseirisvlireddldaaaralheqfqlggedeavvyagtg
r

    Sequence, based on observed residues (ATOM records):
    >3ab4A (A:)
alvvqkyggsslesaerirnvaerivatkkagndvvvvcsamgdttdellelaaavnpvp
paremdmlltagerisnalvamaieslgaeaqsftgsvtpgrvrealdegkicivggsdt
tavalaaalnadvceiysdvdgvytadprivpnaqkleklsfeemlelaavgskilvlrs
veyarafnvplrvrssysndpgtliagsmedipveeavltgvatdkseakvtvlgisdkp
geaakvfraladaeinidmvlqnvfsdgttditftcprsdgrrameilkklqvqgnwtnv
lyddqvgkvslvgagmkshpgvtaefmealrdvnvnielistseirisvlireddldaaa
ralheqfqlg

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3ab4B (B:)
meeavltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnvfsvedgttd
itftcprsdgrrameilkklqvqgnwtnvlyddqvgkvslvgagmkshpgvtaefmealr
dvnvnielistseirisvlireddldaaaralheqfqlggedeavvyagtgrhhhhhh

    Sequence, based on observed residues (ATOM records):
    >3ab4B (B:)
vltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnvfsdgttditftcp
rsdgrrameilkklqvgnwtnvlyddqvgkvslvgagmkshpgvtaefmealrdvnvnie
listseirisvlireddldaaaralheqfqlggedea

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3ab4C (C:)
malvvqkyggsslesaerirnvaerivatkkagndvvvvcsamgdttdellelaaavnpv
pparemdmlltagerisnalvamaieslgaeaqsftgsqagvltterhgnarivdvtpgr
vrealdegkicivagfqgvnketrdvttlgrggsdttavalaaalnadvceiysdvdgvy
tadprivpnaqkleklsfeemlelaavgskilvlrsveyarafnvplrvrssysndpgtl
iagsmedipveeavltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnv
fsvedgttditftcprsdgrrameilkklqvqgnwtnvlyddqvgkvslvgagmkshpgv
taefmealrdvnvnielistseirisvlireddldaaaralheqfqlggedeavvyagtg
r

    Sequence, based on observed residues (ATOM records):
    >3ab4C (C:)
alvvqkyggsslesaerirnvaerivatkkagndvvvvcsamgdttdellelaaavnpvp
paremdmlltagerisnalvamaieslgaeaqsfttpgrvrealdegkicivaggsdtta
valaaalnadvceiysdvdgvytadprivpnaqkleklsfeemlelaavgskilvlrsve
yarafnvplrvrssysndpgtliagsmedipveeavltgvatdkseakvtvlgisdkpge
aakvfraladaeinidmvlqnvdgttditftcprsdgrrameilkklqvqgnwtnvlydd
qvgkvslvgagmkshpgvtaefmealrdvnvnielistseirisvlireddldaaaralh
eqfqlgg

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3ab4D (D:)
meeavltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnvfsvedgttd
itftcprsdgrrameilkklqvqgnwtnvlyddqvgkvslvgagmkshpgvtaefmealr
dvnvnielistseirisvlireddldaaaralheqfqlggedeavvyagtgrhhhhhh

    Sequence, based on observed residues (ATOM records):
    >3ab4D (D:)
eavltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnvfdgttditftc
prsdgrrameilkklqvnwtnvlyddqvgkvslvgagmkshpgvtaefmealrdvnvnie
listseirisvlireddldaaaralheqfq

  • Chain 'E':
    Sequence, based on SEQRES records:
    >3ab4E (E:)
malvvqkyggsslesaerirnvaerivatkkagndvvvvcsamgdttdellelaaavnpv
pparemdmlltagerisnalvamaieslgaeaqsftgsqagvltterhgnarivdvtpgr
vrealdegkicivagfqgvnketrdvttlgrggsdttavalaaalnadvceiysdvdgvy
tadprivpnaqkleklsfeemlelaavgskilvlrsveyarafnvplrvrssysndpgtl
iagsmedipveeavltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnv
fsvedgttditftcprsdgrrameilkklqvqgnwtnvlyddqvgkvslvgagmkshpgv
taefmealrdvnvnielistseirisvlireddldaaaralheqfqlggedeavvyagtg
r

    Sequence, based on observed residues (ATOM records):
    >3ab4E (E:)
alvvqkyggsslesaerirnvaerivatkkagndvvvvcsamgdttdellelaaavnpvp
paremdmlltagerisnalvamaieslgaeaqsftgtpgrvrealdegkicivagflgrg
gsdttavalaaalnadvceiysdvdgvytadprivpnaqkleklsfeemlelaavgskil
vlrsveyarafnvplrvrssysndpgtliagsmedipveeavltgvatdkseakvtvlgi
sdkpgeaakvfraladaeinidmvlqnttditftcprsdgrrameilkklqgnwtnvlyd
dqvgkvslvgagmkshpgvtaefmealrdvnvnielistseirisvlireddldaaaral
heqfqlgg

  • Chain 'F':
    Sequence, based on SEQRES records:
    >3ab4F (F:)
meeavltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnvfsvedgttd
itftcprsdgrrameilkklqvqgnwtnvlyddqvgkvslvgagmkshpgvtaefmealr
dvnvnielistseirisvlireddldaaaralheqfqlggedeavvyagtgrhhhhhh

    Sequence, based on observed residues (ATOM records):
    >3ab4F (F:)
avltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnvfdgttditftcp
rsdgrrameilkklqvqwtnvlyddqvgkvslvgagmkshpgvtaefmealrdvnvniel
istseirisvlireddldaaaralheqf

  • Chain 'G':
    Sequence, based on SEQRES records:
    >3ab4G (G:)
malvvqkyggsslesaerirnvaerivatkkagndvvvvcsamgdttdellelaaavnpv
pparemdmlltagerisnalvamaieslgaeaqsftgsqagvltterhgnarivdvtpgr
vrealdegkicivagfqgvnketrdvttlgrggsdttavalaaalnadvceiysdvdgvy
tadprivpnaqkleklsfeemlelaavgskilvlrsveyarafnvplrvrssysndpgtl
iagsmedipveeavltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnv
fsvedgttditftcprsdgrrameilkklqvqgnwtnvlyddqvgkvslvgagmkshpgv
taefmealrdvnvnielistseirisvlireddldaaaralheqfqlggedeavvyagtg
r

    Sequence, based on observed residues (ATOM records):
    >3ab4G (G:)
alvvqkyggsslesaerirnvaerivatkkagndvvvvcsamgdttdellelaaavnpvp
paremdmlltagerisnalvamaieslgaeaqsftrvrealdegkicivaggsdttaval
aaalnadvceiysdvdgvytadprivpnaqkleklsfeemlelaavgskilvlrsveyar
afnvplrvrssysndpgtliagsmedipvavltgvatdkseakvtvlgisdkpgeaakvf
raladaeinidmvlqnvfttditftcprsdgrrameilkklqvqwtnvlyddqvgkvslv
gagmkshpgvtaefmealrdvnvnielistseirisvlireddldaaaralheqfql

  • Chain 'H':
    Sequence, based on SEQRES records:
    >3ab4H (H:)
meeavltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnvfsvedgttd
itftcprsdgrrameilkklqvqgnwtnvlyddqvgkvslvgagmkshpgvtaefmealr
dvnvnielistseirisvlireddldaaaralheqfqlggedeavvyagtgrhhhhhh

    Sequence, based on observed residues (ATOM records):
    >3ab4H (H:)
ltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnvfsvedgttditftc
prsdgrrameilkklqvqgnwtnvlyddqvgkvslvgagmkpgvtaefmealrdvnvnie
listseirisvlireddldaaaralheqfql

  • Chain 'I':
    Sequence, based on SEQRES records:
    >3ab4I (I:)
malvvqkyggsslesaerirnvaerivatkkagndvvvvcsamgdttdellelaaavnpv
pparemdmlltagerisnalvamaieslgaeaqsftgsqagvltterhgnarivdvtpgr
vrealdegkicivagfqgvnketrdvttlgrggsdttavalaaalnadvceiysdvdgvy
tadprivpnaqkleklsfeemlelaavgskilvlrsveyarafnvplrvrssysndpgtl
iagsmedipveeavltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnv
fsvedgttditftcprsdgrrameilkklqvqgnwtnvlyddqvgkvslvgagmkshpgv
taefmealrdvnvnielistseirisvlireddldaaaralheqfqlggedeavvyagtg
r

    Sequence, based on observed residues (ATOM records):
    >3ab4I (I:)
alvvqkyggsslesaerirnvaerivatkkagndvvvvcsamgdttdellelaaavnpvp
paremdmlltagerisnalvamaieslgaeaqsftpgrvrealdegkicivagsdttava
laaalnadvceiysdvdgvytadprivpnaqkleklsfeemlelaavgskilvlrsveya
rafnvplrvrssysndpgtliagsmedipvavltgvatdkseakvtvlgisdkpgeaakv
fraladaeinidmvlqnvfsttditftcprsdgrrameilkklqvqgnwtnvlyddqvgk
vslvgagmkshpgvtaefmealrdvnvnielistseirisvlireddldaaaralheqfq

  • Chain 'J':
    Sequence, based on SEQRES records:
    >3ab4J (J:)
meeavltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnvfsvedgttd
itftcprsdgrrameilkklqvqgnwtnvlyddqvgkvslvgagmkshpgvtaefmealr
dvnvnielistseirisvlireddldaaaralheqfqlggedeavvyagtgrhhhhhh

    Sequence, based on observed residues (ATOM records):
    >3ab4J (J:)
vatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnvfsttditftcprsdgrr
ameilkklqvqwtnvlyddqvgkvslvggvtaefmealrdvnvnielistseirisvlir
eddldaaaralh

  • Chain 'K':
    Sequence, based on SEQRES records:
    >3ab4K (K:)
malvvqkyggsslesaerirnvaerivatkkagndvvvvcsamgdttdellelaaavnpv
pparemdmlltagerisnalvamaieslgaeaqsftgsqagvltterhgnarivdvtpgr
vrealdegkicivagfqgvnketrdvttlgrggsdttavalaaalnadvceiysdvdgvy
tadprivpnaqkleklsfeemlelaavgskilvlrsveyarafnvplrvrssysndpgtl
iagsmedipveeavltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnv
fsvedgttditftcprsdgrrameilkklqvqgnwtnvlyddqvgkvslvgagmkshpgv
taefmealrdvnvnielistseirisvlireddldaaaralheqfqlggedeavvyagtg
r

    Sequence, based on observed residues (ATOM records):
    >3ab4K (K:)
alvvqkyggsslesaerirnvaerivatkkagndvvvvcsamgdttdellelaaavnpvp
paremdmlltagerisnalvamaieslgaeaqsftgrvrealdegkicivatrdvttlgr
ggsdttavalaaalnadvceiysdvdgvytadprivpnaqkleklsfeemlelaavgski
lvlrsveyarafnvplrvrssysndpgtliagsmedipveeavltgvatdkseakvtvlg
isdkpgeaakvfraladaeinidmvlqnvfgttditftcprsdgrrameilkklqvqgnw
tnvlyddqvgkvslvgagmkshpgvtaefmealrdvnvnielistseirisvlireddld
aaaralheqfqlg

  • Chain 'L':
    Sequence, based on SEQRES records:
    >3ab4L (L:)
meeavltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnvfsvedgttd
itftcprsdgrrameilkklqvqgnwtnvlyddqvgkvslvgagmkshpgvtaefmealr
dvnvnielistseirisvlireddldaaaralheqfqlggedeavvyagtgrhhhhhh

    Sequence, based on observed residues (ATOM records):
    >3ab4L (L:)
eeavltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnvfsvedgttdi
tftcprsdgrrameilkklqvnwtnvlyddqvgkvslvgagmkshpgvtaefmealrdvn
vnielistseirisvlireddldaaaralheqfqlg

  • Chain 'M':
    Sequence, based on SEQRES records:
    >3ab4M (M:)
malvvqkyggsslesaerirnvaerivatkkagndvvvvcsamgdttdellelaaavnpv
pparemdmlltagerisnalvamaieslgaeaqsftgsqagvltterhgnarivdvtpgr
vrealdegkicivagfqgvnketrdvttlgrggsdttavalaaalnadvceiysdvdgvy
tadprivpnaqkleklsfeemlelaavgskilvlrsveyarafnvplrvrssysndpgtl
iagsmedipveeavltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnv
fsvedgttditftcprsdgrrameilkklqvqgnwtnvlyddqvgkvslvgagmkshpgv
taefmealrdvnvnielistseirisvlireddldaaaralheqfqlggedeavvyagtg
r

    Sequence, based on observed residues (ATOM records):
    >3ab4M (M:)
alvvqkyggsslesaerirnvaerivatkkagndvvvvcsamgdttdellelaaavnpvp
paremdmlltagerisnalvamaieslgaeaqsftgdvtpgrvrealdegkicivagfvt
tlgrggsdttavalaaalnadvceiysdvdgvytadprivpnaqkleklsfeemlelaav
gskilvlrsveyarafnvplrvrssysndpgtliagsmedipveeavltgvatdkseakv
tvlgisdkpgeaakvfraladaeinidmvlqnvfgttditftcprsdgrrameilkklqv
qgnwtnvlyddqvgkvslvgagmkshpgvtaefmealrdvnvnielistseirisvlire
ddldaaaralheqfqlg

  • Chain 'N':
    Sequence, based on SEQRES records:
    >3ab4N (N:)
meeavltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnvfsvedgttd
itftcprsdgrrameilkklqvqgnwtnvlyddqvgkvslvgagmkshpgvtaefmealr
dvnvnielistseirisvlireddldaaaralheqfqlggedeavvyagtgrhhhhhh

    Sequence, based on observed residues (ATOM records):
    >3ab4N (N:)
avltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnvfsvedgttditf
tcprsdgrrameilkklqvqgnwtnvlyddqvgkvslvgagmkshpgvtaefmealrdvn
vnielistseirisvlireddldaaaralheqfql

  • Chain 'O':
    Sequence, based on SEQRES records:
    >3ab4O (O:)
malvvqkyggsslesaerirnvaerivatkkagndvvvvcsamgdttdellelaaavnpv
pparemdmlltagerisnalvamaieslgaeaqsftgsqagvltterhgnarivdvtpgr
vrealdegkicivagfqgvnketrdvttlgrggsdttavalaaalnadvceiysdvdgvy
tadprivpnaqkleklsfeemlelaavgskilvlrsveyarafnvplrvrssysndpgtl
iagsmedipveeavltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnv
fsvedgttditftcprsdgrrameilkklqvqgnwtnvlyddqvgkvslvgagmkshpgv
taefmealrdvnvnielistseirisvlireddldaaaralheqfqlggedeavvyagtg
r

    Sequence, based on observed residues (ATOM records):
    >3ab4O (O:)
alvvqkyggsslesaerirnvaerivatkkagndvvvvcsamgdttdellelaaavnpvp
paremdmlltagerisnalvamaieslgaeaqsftdvtpgrvrealdegkicivarggsd
ttavalaaalnadvceiysdvdgvytadprivpnaqkleklsfeemlelaavgskilvlr
sveyarafnvplrvrssysndpgtliagsmedipveeavltgvatdkseakvtvlgisdk
pgeaakvfraladaeinidmvlqndgttditftcprsdgrrameilkkqgnwtnvlyddq
vgkvslvgagmkshpgvtaefmealrdvnvnielistseirisvlireddldaaaralhe
qfql

  • Chain 'P':
    Sequence, based on SEQRES records:
    >3ab4P (P:)
meeavltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnvfsvedgttd
itftcprsdgrrameilkklqvqgnwtnvlyddqvgkvslvgagmkshpgvtaefmealr
dvnvnielistseirisvlireddldaaaralheqfqlggedeavvyagtgrhhhhhh

    Sequence, based on observed residues (ATOM records):
    >3ab4P (P:)
vltgvatdkseakvtvlgisdkpgeaakvfraladaeinidmvlqnvfsvedgttditft
cprsdgrrameilkklqvqgnwtnvlyddqvgkvslvgahpgvtaefmealrdvnvniel
istseirisvlireddldaaaralheqfq