PDB entry 3a77

View 3a77 on RCSB PDB site
Description: The crystal structure of phosphorylated IRF-3
Class: transcription
Keywords: phosphorylated protein, Activator, Antiviral defense, DNA-binding, Host-virus interaction, Nucleus, Phosphoprotein, Transcription, Transcription regulation
Deposited on 2009-09-17, released 2010-08-04
The last revision prior to the SCOPe 2.06 freeze date was dated 2010-08-04, with a file datestamp of 2010-07-30.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.194
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Interferon regulatory factor 3
    Species: Homo sapiens [TaxId:9606]
    Gene: IRF3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3a77a_
  • Chain 'B':
    Compound: Interferon regulatory factor 3
    Species: Homo sapiens [TaxId:9606]
    Gene: IRF3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3a77b_
  • Chain 'C':
    Compound: Interferon regulatory factor 3
    Species: Homo sapiens [TaxId:9606]
    Gene: IRF3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3a77c_
  • Chain 'D':
    Compound: Interferon regulatory factor 3
    Species: Homo sapiens [TaxId:9606]
    Gene: IRF3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3a77d_
  • Heterogens: ACY, MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3a77A (A:)
gamenplkrllvpgeewefevtafyrgrqvfqqtiscpeglrlvgsevgdrtlpgwpvtl
pdpgmsltdrgvmsyvrhvlsclggglalwragqwlwaqrlghchtywavseellpnsgh
gpdgevpkdkeggvfdlgpfivdlitftegsgrspryalwfcvgeswpqdqpwtkrlvmv
kvvptclralvemarvggasslentvdlhisnshplsltsdqykaylqdlvegmdfqgpg
es

    Sequence, based on observed residues (ATOM records): (download) 
    >3a77A (A:)
enplkrllvpgeewefevtafyrgrqvfqqtiscpeglrlvtlpgwpvtlpdpgmsltdr
gvmsyvrhvlsclggglalwragqwlwaqrlghchtywavseellpnsghgpdgevpkdk
eggvfdlgpfivdlitftegsgrspryalwfcvgeswpqdqpwtkrlvmvkvvptclral
vemarvggasslentvdlhisnshplsltsdqykaylqdlvegmdfqgpges

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3a77B (B:)
gamenplkrllvpgeewefevtafyrgrqvfqqtiscpeglrlvgsevgdrtlpgwpvtl
pdpgmsltdrgvmsyvrhvlsclggglalwragqwlwaqrlghchtywavseellpnsgh
gpdgevpkdkeggvfdlgpfivdlitftegsgrspryalwfcvgeswpqdqpwtkrlvmv
kvvptclralvemarvggasslentvdlhisnshplsltsdqykaylqdlvegmdfqgpg
es

    Sequence, based on observed residues (ATOM records): (download) 
    >3a77B (B:)
enplkrllvpgeewefevtafyrgrqvfqqtiscpeglrlvgsetlpgwpvtlpdpgmsl
tdrgvmsyvrhvlsclggglalwragqwlwaqrlghchtywavseellpnsghgpdgevp
kdkeggvfdlgpfivdlitftegsgrspryalwfcvgeswpqdqpwtkrlvmvkvvptcl
ralvemarvggasslentvdlhisnshplsltsdqykaylqdlvegmdfqgpge

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3a77C (C:)
gamenplkrllvpgeewefevtafyrgrqvfqqtiscpeglrlvgsevgdrtlpgwpvtl
pdpgmsltdrgvmsyvrhvlsclggglalwragqwlwaqrlghchtywavseellpnsgh
gpdgevpkdkeggvfdlgpfivdlitftegsgrspryalwfcvgeswpqdqpwtkrlvmv
kvvptclralvemarvggasslentvdlhisnshplsltsdqykaylqdlvegmdfqgpg
es

    Sequence, based on observed residues (ATOM records): (download) 
    >3a77C (C:)
enplkrllvpgeewefevtafyrgrqvfqqtiscpeglrlvgstlpgwpvtlpdpgmslt
drgvmsyvrhvlsclggglalwragqwlwaqrlghchtywavseellpnsghgpdgevpk
dkeggvfdlgpfivdlitftegsgrspryalwfcvgeswpqdqpwtkrlvmvkvvptclr
alvemarvggasslentvdlhisnshplsltsdqykaylqdlvegmdfqgpge

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3a77D (D:)
gamenplkrllvpgeewefevtafyrgrqvfqqtiscpeglrlvgsevgdrtlpgwpvtl
pdpgmsltdrgvmsyvrhvlsclggglalwragqwlwaqrlghchtywavseellpnsgh
gpdgevpkdkeggvfdlgpfivdlitftegsgrspryalwfcvgeswpqdqpwtkrlvmv
kvvptclralvemarvggasslentvdlhisnshplsltsdqykaylqdlvegmdfqgpg
es

    Sequence, based on observed residues (ATOM records): (download) 
    >3a77D (D:)
nplkrllvpgeewefevtafyrgrqvfqqtiscpeglrlvglpgwpvtlpdpgmsltdrg
vmsyvrhvlsclggglalwragqwlwaqrlghchtywavseellpnsghgpdgevpkdke
ggvfdlgpfivdlitftegsgrspryalwfcvgeswpqdqpwtkrlvmvkvvptclralv
emarvggasslentvdlhisnshplsltsdqykaylqdlvegmdfqgpge