PDB entry 3a74

View 3a74 on RCSB PDB site
Description: Lysyl-tRNA synthetase from Bacillus stearothermophilus complexed with Diadenosine Tetraphosphate (AP4A)
Class: ligase
Keywords: aminoacyl tRNA synthetase, LIGASE, PROTEIN BIOSYNTHESIS, Aminoacyl-tRNA synthetase, ATP-binding, Magnesium, Metal-binding, Nucleotide-binding
Deposited on 2009-09-13, released 2010-09-22
The last revision prior to the SCOPe 2.03 freeze date was dated 2010-09-22, with a file datestamp of 2010-09-17.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.207
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: lysyl-tRNA synthetase
    Species: Geobacillus stearothermophilus [TaxId:1422]
    Gene: LYSS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3a74a1, d3a74a2
  • Chain 'B':
    Compound: lysyl-tRNA synthetase
    Species: Geobacillus stearothermophilus [TaxId:1422]
    Gene: LYSS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3a74b1, d3a74b2
  • Chain 'C':
    Compound: lysyl-tRNA synthetase
    Species: Geobacillus stearothermophilus [TaxId:1422]
    Gene: LYSS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3a74c1, d3a74c2
  • Chain 'D':
    Compound: lysyl-tRNA synthetase
    Species: Geobacillus stearothermophilus [TaxId:1422]
    Gene: LYSS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3a74d1, d3a74d2
  • Heterogens: B4P, LYN, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3a74A (A:)
sheelndqlrvrreklkkieelgvdpfgkrferthkaeelfelygdlskeeleeqqieva
vagrimtkrgmgkagfahiqdvtgqiqiyvrqddvgeqqyelfkisdlgdivgvrgtmfk
tkvgelsikvssyefltkalrplpekyhglkdieqryrqryldlimnpeskktfitrsli
iqsmrryldshgylevetpmmhavaggaaarpfithhnaldmtlymriaielhlkrlivg
glekvyeigrvfrnegistrhnpeftmlelyeayadfrdimkltenliahiatevlgttk
iqygehlvdltpewrrlhmvdaikeyvgvdfwrqmsdeearelakehgvevaphmtfghi
vneffeqkvedkliqptfiyghpveisplakknpddprftdrfelfivgrehanafteln
dpidqrqrfeeqlkereqgndeahemdedflealeygmpptgglgigvdrlvmlltnsps
irdvllfpqmrhk

    Sequence, based on observed residues (ATOM records): (download) 
    >3a74A (A:)
elndqlrvrreklkkieelgvdpfgkrferthkaeelfelygdlskeeleeqqievavag
rimtkrgmgkagfahiqdvtgqiqiyvrqddvgeqqyelfkisdlgdivgvrgtmfktkv
gelsikvssyefltkalrplpekdieqryrqryldlimnpeskktfitrsliiqsmrryl
dshgylevetpmmhavaggaaarpfithhnaldmtlymriaielhlkrlivgglekvyei
grvfrnegistrhnpeftmlelyeayadfrdimkltenliahiatevlgttkiqygehlv
dltpewrrlhmvdaikeyvgvdfwrqmsdeearelakehgvevaphmtfghivneffeqk
vedkliqptfiyghpveisplakknpddprftdrfelfivgrehanaftelndpidqrqr
feeqlkereqgndeahemdedflealeygmpptgglgigvdrlvmlltnspsirdvllfp
qmrh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3a74B (B:)
sheelndqlrvrreklkkieelgvdpfgkrferthkaeelfelygdlskeeleeqqieva
vagrimtkrgmgkagfahiqdvtgqiqiyvrqddvgeqqyelfkisdlgdivgvrgtmfk
tkvgelsikvssyefltkalrplpekyhglkdieqryrqryldlimnpeskktfitrsli
iqsmrryldshgylevetpmmhavaggaaarpfithhnaldmtlymriaielhlkrlivg
glekvyeigrvfrnegistrhnpeftmlelyeayadfrdimkltenliahiatevlgttk
iqygehlvdltpewrrlhmvdaikeyvgvdfwrqmsdeearelakehgvevaphmtfghi
vneffeqkvedkliqptfiyghpveisplakknpddprftdrfelfivgrehanafteln
dpidqrqrfeeqlkereqgndeahemdedflealeygmpptgglgigvdrlvmlltnsps
irdvllfpqmrhk

    Sequence, based on observed residues (ATOM records): (download) 
    >3a74B (B:)
elndqlrvrreklkkieelgvdpfgkrferthkaeelfelygdlskeeleeqqievavag
rimtkrgmgkagfahiqdvtgqiqiyvrqddvgeqqyelfkisdlgdivgvrgtmfktkv
gelsikvssyefltkalrplpekdieqryrqryldlimnpeskktfitrsliiqsmrryl
dshgylevetpmmhavaggaaarpfithhnaldmtlymriaielhlkrlivgglekvyei
grvfrnegistrhnpeftmlelyeayadfrdimkltenliahiatevlgttkiqygehlv
dltpewrrlhmvdaikeyvgvdfwrqmsdeearelakehgvevaphmtfghivneffeqk
vedkliqptfiyghpveisplakknpddprftdrfelfivgrehanaftelndpidqrqr
feeqlkereqgndeahemdedflealeygmpptgglgigvdrlvmlltnspsirdvllfp
qmrh

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3a74C (C:)
sheelndqlrvrreklkkieelgvdpfgkrferthkaeelfelygdlskeeleeqqieva
vagrimtkrgmgkagfahiqdvtgqiqiyvrqddvgeqqyelfkisdlgdivgvrgtmfk
tkvgelsikvssyefltkalrplpekyhglkdieqryrqryldlimnpeskktfitrsli
iqsmrryldshgylevetpmmhavaggaaarpfithhnaldmtlymriaielhlkrlivg
glekvyeigrvfrnegistrhnpeftmlelyeayadfrdimkltenliahiatevlgttk
iqygehlvdltpewrrlhmvdaikeyvgvdfwrqmsdeearelakehgvevaphmtfghi
vneffeqkvedkliqptfiyghpveisplakknpddprftdrfelfivgrehanafteln
dpidqrqrfeeqlkereqgndeahemdedflealeygmpptgglgigvdrlvmlltnsps
irdvllfpqmrhk

    Sequence, based on observed residues (ATOM records): (download) 
    >3a74C (C:)
elndqlrvrreklkkieelgvdpfgkrferthkaeelfelygdlskeeleeqqievavag
rimtkrgmgkagfahiqdvtgqiqiyvrqddvgeqqyelfkisdlgdivgvrgtmfktkv
gelsikvssyefltkalrplpekdieqryrqryldlimnpeskktfitrsliiqsmrryl
dshgylevetpmmhavaggaaarpfithhnaldmtlymriaielhlkrlivgglekvyei
grvfrnegistrhnpeftmlelyeayadfrdimkltenliahiatevlgttkiqygehlv
dltpewrrlhmvdaikeyvgvdfwrqmsdeearelakehgvevaphmtfghivneffeqk
vedkliqptfiyghpveisplakknpddprftdrfelfivgrehanaftelndpidqrqr
feeqlkereqgndeahemdedflealeygmpptgglgigvdrlvmlltnspsirdvllfp
qmrh

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3a74D (D:)
sheelndqlrvrreklkkieelgvdpfgkrferthkaeelfelygdlskeeleeqqieva
vagrimtkrgmgkagfahiqdvtgqiqiyvrqddvgeqqyelfkisdlgdivgvrgtmfk
tkvgelsikvssyefltkalrplpekyhglkdieqryrqryldlimnpeskktfitrsli
iqsmrryldshgylevetpmmhavaggaaarpfithhnaldmtlymriaielhlkrlivg
glekvyeigrvfrnegistrhnpeftmlelyeayadfrdimkltenliahiatevlgttk
iqygehlvdltpewrrlhmvdaikeyvgvdfwrqmsdeearelakehgvevaphmtfghi
vneffeqkvedkliqptfiyghpveisplakknpddprftdrfelfivgrehanafteln
dpidqrqrfeeqlkereqgndeahemdedflealeygmpptgglgigvdrlvmlltnsps
irdvllfpqmrhk

    Sequence, based on observed residues (ATOM records): (download) 
    >3a74D (D:)
elndqlrvrreklkkieelgvdpfgkrferthkaeelfelygdlskeeleeqqievavag
rimtkrgmgkagfahiqdvtgqiqiyvrqddvgeqqyelfkisdlgdivgvrgtmfktkv
gelsikvssyefltkalrplpekdieqryrqryldlimnpeskktfitrsliiqsmrryl
dshgylevetpmmhavaggaaarpfithhnaldmtlymriaielhlkrlivgglekvyei
grvfrnegistrhnpeftmlelyeayadfrdimkltenliahiatevlgttkiqygehlv
dltpewrrlhmvdaikeyvgvdfwrqmsdeearelakehgvevaphmtfghivneffeqk
vedkliqptfiyghpveisplakknpddprftdrfelfivgrehanaftelndpidqrqr
feeqlkereqgndeahemdedflealeygmpptgglgigvdrlvmlltnspsirdvllfp
qmrh