PDB entry 3a6p
View 3a6p on RCSB PDB site
Description: Crystal structure of Exportin-5:RanGTP:pre-miRNA complex
Class: protein transport/nuclear protein/RNA
Keywords: EXPORTIN-5, PRE-MICRORNA, RANGTP, NUCLEAREXPORT, IMPORTIN-BETA FAMILY, Alternative splicing, Cytoplasm, Nucleus, Phosphoprotein, Polymorphism, Protein transport, RNA-binding, RNA-mediated gene silencing, Transport, tRNA-binding, Acetylation, Cell cycle, Cell division, GTP-binding, Isopeptide bond, Mitosis, Nucleotide-binding, Ubl conjugation, PROTEIN TRANSPORT/NUCLEAR PROTEIN/RNA COMPLEX
Deposited on
2009-09-07, released
2009-12-08
The last revision prior to the SCOPe 2.01 freeze date was dated
2009-12-08, with a file datestamp of
2009-12-04.
Experiment type: XRAY
Resolution: 2.92 Å
R-factor: 0.251
AEROSPACI score: 0.2
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Exportin-5
Species: Homo sapiens [TaxId:9606]
Gene: XPO5, KIAA1291, RANBP21
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: 13-mer peptide
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Chain 'C':
Compound: GTP-binding nuclear protein ran
Species: Canis lupus familiaris [TaxId:9615]
Gene: RAN
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d3a6pc_ - Chain 'D':
Compound: pre-microRNA
- Chain 'E':
Compound: pre-microRNA
- Chain 'F':
Compound: Exportin-5
Species: Homo sapiens [TaxId:9606]
Gene: XPO5, KIAA1291, RANBP21
Database cross-references and differences (RAF-indexed):
- Chain 'G':
Compound: 13-mer peptide
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Chain 'H':
Compound: GTP-binding nuclear protein ran
Species: Canis lupus familiaris [TaxId:9615]
Gene: RAN
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d3a6ph_ - Chain 'I':
Compound: pre-microRNA
- Chain 'J':
Compound: pre-microRNA
- Heterogens: GTP, MG
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
No sequence available.
- Chain 'C':
Sequence, based on SEQRES records: (download)
>3a6pC (C:)
maaqgepqvqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpik
fnvwdtagqekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlc
gnkvdikdrkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlefvamp
alappevvmdpalaaqyehdlevaqttalpdedddl
Sequence, based on observed residues (ATOM records): (download)
>3a6pC (C:)
pqvqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpikfnvwdt
agqekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkvdi
kdrkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlef
- Chain 'D':
No sequence available.
- Chain 'E':
No sequence available.
- Chain 'F':
No sequence available.
- Chain 'G':
No sequence available.
- Chain 'H':
Sequence, based on SEQRES records: (download)
>3a6pH (H:)
maaqgepqvqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpik
fnvwdtagqekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlc
gnkvdikdrkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlefvamp
alappevvmdpalaaqyehdlevaqttalpdedddl
Sequence, based on observed residues (ATOM records): (download)
>3a6pH (H:)
pqvqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpikfnvwdt
agqekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkvdi
kdrkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlef
- Chain 'I':
No sequence available.
- Chain 'J':
No sequence available.