PDB entry 3a3y

View 3a3y on RCSB PDB site
Description: Crystal structure of the sodium-potassium pump with bound potassium and ouabain
Class: hydrolase/transport protein
Keywords: MEMBRANE PROTEIN, ION PUMP, ATPASE, K+ BINDING, OUABAIN BINDING, HALOACID DEHYDROGENEASE SUPERFAMILY, PHOSPHATE ANALOGUE, ATP-BINDING, HYDROLASE, ION TRANSPORT, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, HYDROLASE-TRANSPORT PROTEIN COMPLEX, Membrane, Transmembrane, Transport
Deposited on 2009-06-23, released 2009-09-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Na, K-ATPase alpha subunit
    Species: Squalus acanthias [TaxId:7797]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3a3ya1, d3a3ya2, d3a3ya3, d3a3ya4
  • Chain 'B':
    Compound: Na+,K+-ATPase beta subunit
    Species: Squalus acanthias [TaxId:7797]
    Database cross-references and differences (RAF-indexed):
    • PDB 3A3Y (Start-304)
    Domains in SCOPe 2.08: d3a3yb1, d3a3yb2
  • Chain 'G':
    Compound: Phospholemman-like protein
    Species: Squalus acanthias [TaxId:7797]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3a3yg_
  • Heterogens: MF4, MG, K, OBN, CLR, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3a3yA (A:)
mgkgtasdkyepaatsenatkskkkgkkdkidkkrdldelkkevsmddhklsldelhnky
gtdltrgltnarakeilardgpnsltpppttpewikfcrqlfggfsillwigailcflay
giqaatedepandnlylgvvlstvvivtgcfsyyqeakssrimdsfknmvpqqalvirdg
ekstinaefvvagdlvevkggdripadlriisahgckvdnssltgesepqtrspefssen
pletrniaffstncvegtargvvvytgdrtvmgriatlasglevgrtpiaieiehfihii
tgvavflgvsffilslilgyswleavifligiivanvpegllatvtvcltltakrmarkn
clvknleavetlgststicsdktgtltqnrmtvahmwfdnqiheadttenqsgaafdkts
atwsalsriaalcnravfqagqdnvpilkrsvagdasesallkcielccgsvqgmrdrnp
kiveipfnstnkyqlsihenekssesryllvmkgaperildrcstillngaeeplkedmk
eafqnaylelgglgervlgfchfalpedkynegypfdadepnfpttdlcfvglmamidpp
raavpdavgkcrsagikvimvtgdhpitakaiakgvgiisegnetiediaarlnipigqv
nprdakacvvhgsdlkdlstevlddilhyhteivfartspqqkliivegcqrqgaivavt
gdgvndspalkkadigvamgisgsdvskqaadmillddnfasivtgveegrlifdnlkks
iaytltsnipeitpflvfiignvplplgtvtilcidlgtdmvpaislayeqaesdimkrq
prnpktdklvnerlismaygqigmiqalggffsyfvilaengflpmdligkrvrwddrwi
sdvedsfgqqwtyeqrkiveftchtsffisivvvqwadliicktrrnsifqqgmknkili
fglfeetalaaflsycpgtdvalrmyplkpswwfcafpysliiflydemrrfiirrspgg
wveqetyy

    Sequence, based on observed residues (ATOM records): (download) 
    >3a3yA (A:)
ldelkkevsmddhklsldelhnkygtdltrgltnarakeilardgpnsltpppttpewik
fcrqlfggfsillwigailcflaygiqaatedepandnlylgvvlstvvivtgcfsyyqe
akssrimdsfknmvpqqalvirdgekstinaefvvagdlvevkggdripadlriisahgc
kvdnssltgesepqtrspefssenpletrniaffstncvegtargvvvytgdrtvmgria
tlasglevgrtpiaieiehfihiitgvavflgvsffilslilgyswleavifligiivan
vpegllatvtvcltltakrmarknclvknleavetlgststicsdktgtltqnrmtvahm
wfdnqiheadttenqsgaafdktsatwsalsriaalcnravfqagqdnvpilkrsvagda
sesallkcielccgsvqgmrdrnpkiveipfnstnkyqlsihenekssesryllvmkgap
erildrcstillngaeeplkedmkeafqnaylelgglgervlgfchfalpedkynegypf
dadepnfpttdlcfvglmamidppraavpdavgkcrsagikvimvtgdhpitakaiakgv
giisegnetiediaarlnipigqvnprdakacvvhgsdlkdlstevlddilhyhteivfa
rtspqqkliivegcqrqgaivavtgdgvndspalkkadigvamgisgsdvskqaadmill
ddnfasivtgveegrlifdnlkksiaytltsnipeitpflvfiignvplplgtvtilcid
lgtdmvpaislayeqaesdimkrqprnpktdklvnerlismaygqigmiqalggffsyfv
ilaengflpmdligkrvrwddrwisdvedsfgqqwtyeqrkiveftchtsffisivvvqw
adliicktrrnsifqqgmknkilifglfeetalaaflsycpgtdvalrmyplkpswwfca
fpysliiflydemrrfiirrspggwveqetyy

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3a3yB (B:)
margksketdggwkkflwdsekkeflgrtgsswfkiflfylifygclagifigtiqvlll
tlsdfepkyqdrvappglshapyaikteisfsisnpksyesfvksmhklmdlynessqag
nspfedcsdtpadyikrgdlddsqgqkkacrfsrmwlkncsglddttygyaegkpcvvak
lnriigfypkplknttdlpeqlqanynqyvlplrcaakreedrekigsieyfglggyagf
plqyypyygkrlqkkylqpllaiqftnltqnmelrieckvygenidysekdrfrgrfevk
ievks

    Sequence, based on observed residues (ATOM records): (download) 
    >3a3yB (B:)
rtgsswfkiflfylifygclagifigtiqvllltlsdfepkyqdrvappglshapyaikt
eisfsisnpksyesfvksmhklmdlynessqagnspfedcsdtpadyikrgdlddsqgqk
kacrfsrmwlkncgyaegkpcvvaklnriigfypkplknttdlpeqlqanynqyvlplrc
aarekigsieyfglggyagfplqyypyygkrlqkkylqpllaiqftnltqnmelrieckv
ygenidysekdrfrgrfevkievks

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >3a3yG (G:)
mdpegpdnderftydyyrlrvvglivaavlcvigiiillagkcrckfnqnkrtrsnsgta
taqhllqpgeatec

    Sequence, based on observed residues (ATOM records): (download) 
    >3a3yG (G:)
gpdnderftydyyrlrvvglivaavlcvigiiillagk