PDB entry 2zzc

View 2zzc on RCSB PDB site
Description: crystal structure of nadp(h):human thioredoxin reductase i
Deposited on 2009-02-09, released 2009-08-18
The last revision was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thioredoxin reductase 1, cytoplasmic
    Species: Homo sapiens [TaxId:9606]
    Gene: TXNRD1, KDRF
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Thioredoxin reductase 1, cytoplasmic
    Species: Homo sapiens [TaxId:9606]
    Gene: TXNRD1, KDRF
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Thioredoxin reductase 1, cytoplasmic
    Species: Homo sapiens [TaxId:9606]
    Gene: TXNRD1, KDRF
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Thioredoxin reductase 1, cytoplasmic
    Species: Homo sapiens [TaxId:9606]
    Gene: TXNRD1, KDRF
    Database cross-references and differences (RAF-indexed):
  • Heterogens: FAD, NAP, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2zzcA (A:)
mahhhhhhvddddkmngpedlpksydydliiigggsgglaaakeaaqygkkvmvldfvtp
tplgtrwglggtcvnvgcipkklmhqaallgqalqdsrnygwkveetvkhdwdrmieavq
nhigslnwgyrvalrekkvvyenaygqfigphrikatnnkgkekiysaerfliatgerpr
ylgipgdkeycissddlfslpycpgktlvvgasyvalecagflagigldvtvmvrsillr
gfdqdmankigehmeehgikfirqfvpikveqieagtpgrlrvvaqstnseeiiegeynt
vmlaigrdactrkigletvgvkinektgkipvtdeeqtnvpyiyaigdiledkveltpva
iqagrllaqrlyagstvkcdyenvpttvftpleygacglseekavekfgeenievyhsyf
wplewtipsrdnnkcyakiicntkdnervvgfhvlgpnagevtqgfaaalkcgltkkqld
stigihpvcaevfttlsvtkrsgasilqagccg

    Sequence, based on observed residues (ATOM records):
    >2zzcA (A:)
sydydliiigggsgglaaakeaaqygkkvmvldfvtptplgtrwglggtcvnvgcipkkl
mhqaallgqalqdsrnygwkveetvkhdwdrmieavqnhigslnwgyrvalrekkvvyen
aygqfigphrikatnnkgkekiysaerfliatgerprylgipgdkeycissddlfslpyc
pgktlvvgasyvalecagflagigldvtvmvrsillrgfdqdmankigehmeehgikfir
qfvpikveqieagtpgrlrvvaqstnseeiiegeyntvmlaigrdactrkigletvgvki
nektgkipvtdeeqtnvpyiyaigdiledkveltpvaiqagrllaqrlyagstvkcdyen
vpttvftpleygacglseekavekfgeenievyhsyfwplewtipsrdnnkcyakiicnt
kdnervvgfhvlgpnagevtqgfaaalkcgltkkqldstigihpvcaevfttlsvtkrsg
asilq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2zzcB (B:)
mahhhhhhvddddkmngpedlpksydydliiigggsgglaaakeaaqygkkvmvldfvtp
tplgtrwglggtcvnvgcipkklmhqaallgqalqdsrnygwkveetvkhdwdrmieavq
nhigslnwgyrvalrekkvvyenaygqfigphrikatnnkgkekiysaerfliatgerpr
ylgipgdkeycissddlfslpycpgktlvvgasyvalecagflagigldvtvmvrsillr
gfdqdmankigehmeehgikfirqfvpikveqieagtpgrlrvvaqstnseeiiegeynt
vmlaigrdactrkigletvgvkinektgkipvtdeeqtnvpyiyaigdiledkveltpva
iqagrllaqrlyagstvkcdyenvpttvftpleygacglseekavekfgeenievyhsyf
wplewtipsrdnnkcyakiicntkdnervvgfhvlgpnagevtqgfaaalkcgltkkqld
stigihpvcaevfttlsvtkrsgasilqagccg

    Sequence, based on observed residues (ATOM records):
    >2zzcB (B:)
sydydliiigggsgglaaakeaaqygkkvmvldfvtptplgtrwglggtcvnvgcipkkl
mhqaallgqalqdsrnygwkveetvkhdwdrmieavqnhigslnwgyrvalrekkvvyen
aygqfigphrikatnnkgkekiysaerfliatgerprylgipgdkeycissddlfslpyc
pgktlvvgasyvalecagflagigldvtvmvrsillrgfdqdmankigehmeehgikfir
qfvpikveqieagtpgrlrvvaqstnseeiiegeyntvmlaigrdactrkigletvgvki
nektgkipvtdeeqtnvpyiyaigdiledkveltpvaiqagrllaqrlyagstvkcdyen
vpttvftpleygacglseekavekfgeenievyhsyfwplewtipsrdnnkcyakiicnt
kdnervvgfhvlgpnagevtqgfaaalkcgltkkqldstigihpvcaevfttlsvtkrsg
asil

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2zzcC (C:)
mahhhhhhvddddkmngpedlpksydydliiigggsgglaaakeaaqygkkvmvldfvtp
tplgtrwglggtcvnvgcipkklmhqaallgqalqdsrnygwkveetvkhdwdrmieavq
nhigslnwgyrvalrekkvvyenaygqfigphrikatnnkgkekiysaerfliatgerpr
ylgipgdkeycissddlfslpycpgktlvvgasyvalecagflagigldvtvmvrsillr
gfdqdmankigehmeehgikfirqfvpikveqieagtpgrlrvvaqstnseeiiegeynt
vmlaigrdactrkigletvgvkinektgkipvtdeeqtnvpyiyaigdiledkveltpva
iqagrllaqrlyagstvkcdyenvpttvftpleygacglseekavekfgeenievyhsyf
wplewtipsrdnnkcyakiicntkdnervvgfhvlgpnagevtqgfaaalkcgltkkqld
stigihpvcaevfttlsvtkrsgasilqagccg

    Sequence, based on observed residues (ATOM records):
    >2zzcC (C:)
sydydliiigggsgglaaakeaaqygkkvmvldfvtptplgtrwglggtcvnvgcipkkl
mhqaallgqalqdsrnygwkveetvkhdwdrmieavqnhigslnwgyrvalrekkvvyen
aygqfigphrikatnnkgkekiysaerfliatgerprylgipgdkeycissddlfslpyc
pgktlvvgasyvalecagflagigldvtvmvrsillrgfdqdmankigehmeehgikfir
qfvpikveqieagtpgrlrvvaqstnseeiiegeyntvmlaigrdactrkigletvgvki
nektgkipvtdeeqtnvpyiyaigdiledkveltpvaiqagrllaqrlyagstvkcdyen
vpttvftpleygacglseekavekfgeenievyhsyfwplewtipsrdnnkcyakiicnt
kdnervvgfhvlgpnagevtqgfaaalkcgltkkqldstigihpvcaevfttlsvtkrsg
asilq

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2zzcD (D:)
mahhhhhhvddddkmngpedlpksydydliiigggsgglaaakeaaqygkkvmvldfvtp
tplgtrwglggtcvnvgcipkklmhqaallgqalqdsrnygwkveetvkhdwdrmieavq
nhigslnwgyrvalrekkvvyenaygqfigphrikatnnkgkekiysaerfliatgerpr
ylgipgdkeycissddlfslpycpgktlvvgasyvalecagflagigldvtvmvrsillr
gfdqdmankigehmeehgikfirqfvpikveqieagtpgrlrvvaqstnseeiiegeynt
vmlaigrdactrkigletvgvkinektgkipvtdeeqtnvpyiyaigdiledkveltpva
iqagrllaqrlyagstvkcdyenvpttvftpleygacglseekavekfgeenievyhsyf
wplewtipsrdnnkcyakiicntkdnervvgfhvlgpnagevtqgfaaalkcgltkkqld
stigihpvcaevfttlsvtkrsgasilqagccg

    Sequence, based on observed residues (ATOM records):
    >2zzcD (D:)
sydydliiigggsgglaaakeaaqygkkvmvldfvtptplgtrwglggtcvnvgcipkkl
mhqaallgqalqdsrnygwkveetvkhdwdrmieavqnhigslnwgyrvalrekkvvyen
aygqfigphrikatnnkgkekiysaerfliatgerprylgipgdkeycissddlfslpyc
pgktlvvgasyvalecagflagigldvtvmvrsillrgfdqdmankigehmeehgikfir
qfvpikveqieagtpgrlrvvaqstnseeiiegeyntvmlaigrdactrkigletvgvki
nektgkipvtdeeqtnvpyiyaigdiledkveltpvaiqagrllaqrlyagstvkcdyen
vpttvftpleygacglseekavekfgeenievyhsyfwplewtipsrdnnkcyakiicnt
kdnervvgfhvlgpnagevtqgfaaalkcgltkkqldstigihpvcaevfttlsvtkrsg
asil