PDB entry 2zza

View 2zza on RCSB PDB site
Description: Moritella profunda Dihydrofolate reductase complex with NADP+ and Folate
Class: oxidoreductase
Keywords: Dihydrofolate reductase, Folic acid, NADP, deep-sea, high pressure, low temperature, Moritella profunda, piezophilic, psychrophilic, psychropiezophilic, Oxidoreductase
Deposited on 2009-02-06, released 2010-02-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2010-02-23, with a file datestamp of 2010-02-19.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.201
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydrofolate reductase
    Species: Moritella profunda [TaxId:111291]
    Gene: dyrA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q70YQ6 (0-End)
      • see remark 999 (0)
    Domains in SCOPe 2.07: d2zzaa_
  • Chain 'B':
    Compound: dihydrofolate reductase
    Species: Moritella profunda [TaxId:111291]
    Gene: dyrA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q70YQ6 (0-End)
      • see remark 999 (0)
    Domains in SCOPe 2.07: d2zzab_
  • Heterogens: NAP, FOL, 1PE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2zzaA (A:)
vivsmiaalannrvigldnkmpwhlpaelqlfkratlgkpivmgrntfesigrplpgrln
ivlsrqtdyqpegvtvvatledavvaagdveelmiiggatiynqclaaadrlylthielt
tegdtwfpdyeqynwqeiehesyaaddknphnyrfsllervk

    Sequence, based on observed residues (ATOM records): (download) 
    >2zzaA (A:)
vivsmiaalannrvigldnkmpwhlpaelqlfkratlgkpivmgrntfesigrplpgrln
ivlsrqtdyqpegvtvvatledavvaagdveelmiiggatiynqclaaadrlylthielt
tegdtwfpdyeqynwqeiehesyaaddknphnyrfsllerv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2zzaB (B:)
vivsmiaalannrvigldnkmpwhlpaelqlfkratlgkpivmgrntfesigrplpgrln
ivlsrqtdyqpegvtvvatledavvaagdveelmiiggatiynqclaaadrlylthielt
tegdtwfpdyeqynwqeiehesyaaddknphnyrfsllervk

    Sequence, based on observed residues (ATOM records): (download) 
    >2zzaB (B:)
vivsmiaalannrvigldnkmpwhlpaelqlfkratlgkpivmgrntfesigrplpgrln
ivlsrqtdyqpegvtvvatledavvaagdveelmiiggatiynqclaaadrlylthielt
tegdtwfpdyeqynwqeiehesyaaddknphnyrfsllerv