PDB entry 2zz2

View 2zz2 on RCSB PDB site
Description: Orotidine Monophosphate Decarboxylase K72A mutant from M. thermoautotrophicum complexed with 6-cyano-UMP
Class: Lyase
Keywords: OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE (ODCASE), 6-CYANOUMP OMP decarboxylase, OMPDC, OMPDCASE, Decarboxylase, Lyase, Pyrimidine biosynthesis
Deposited on 2009-02-05, released 2009-03-24
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.53 Å
R-factor: 0.161
AEROSPACI score: 0.64 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: orotidine 5'-phosphate decarboxylase
    Species: Methanothermobacter thermautotrophicus [TaxId:145262]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O26232
      • engineered (74)
      • see remark 999 (103)
    Domains in SCOPe 2.05: d2zz2a_
  • Chain 'B':
    Compound: orotidine 5'-phosphate decarboxylase
    Species: Methanothermobacter thermautotrophicus [TaxId:145262]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O26232
      • engineered (74)
      • see remark 999 (103)
    Domains in SCOPe 2.05: d2zz2b_
  • Heterogens: 6CN, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2zz2A (A:)
gshmrsrrvdvmdvmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiia
efrkrfgcriiadfavadipetnekicratfkagadaiivhgfpgadsvraclnvaeemg
revflltemshpgaemfiqgaadeiarmgvdlgvknyvgpstrperlsrlreiigqdsfl
ispgvgaqggdpgetlrfadaiivgrsiyladnpaaaaagiiesikdlripedpaankar
keaelaaataeq

    Sequence, based on observed residues (ATOM records): (download) 
    >2zz2A (A:)
vmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiiaefrkrfgcriiad
favadipetnekicratfkagadaiivhgfpgadsvraclnvaeemgrevflltemshpg
aemfiqgaadeiarmgvdlgvknyvgpstrperlsrlreiigqdsflispgvgaqggdpg
etlrfadaiivgrsiyladnpaaaaagiiesikdl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2zz2B (B:)
gshmrsrrvdvmdvmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiia
efrkrfgcriiadfavadipetnekicratfkagadaiivhgfpgadsvraclnvaeemg
revflltemshpgaemfiqgaadeiarmgvdlgvknyvgpstrperlsrlreiigqdsfl
ispgvgaqggdpgetlrfadaiivgrsiyladnpaaaaagiiesikdlripedpaankar
keaelaaataeq

    Sequence, based on observed residues (ATOM records): (download) 
    >2zz2B (B:)
vmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiiaefrkrfgcriiad
favadipetnekicratfkagadaiivhgfpgadsvraclnvaeemgrevflltemshpg
aemfiqgaadeiarmgvdlgvknyvgpstrperlsrlreiigqdsflispgvgaqggdpg
etlrfadaiivgrsiyladnpaaaaagiiesikdl