PDB entry 2zvx

View 2zvx on RCSB PDB site
Description: Structure of a BPTI-[5,55] variant containing Gly/Val at the 14/38th positions
Class: hydrolase inhibitor
Keywords: protein folding, protein stabilization, protein design, Pharmaceutical, Protease inhibitor, Secreted, Serine protease inhibitor, HYDROLASE INHIBITOR, Disulfide bond
Deposited on 2008-11-24, released 2009-10-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-10-27, with a file datestamp of 2009-10-23.
Experiment type: XRAY
Resolution: 1.09 Å
R-factor: 0.179
AEROSPACI score: 0.87 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pancreatic trypsin inhibitor
    Species: Bos taurus [TaxId:9913]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00974 (0-57)
      • engineered (13)
      • engineered (29)
      • engineered (37)
      • engineered (50-51)
    Domains in SCOPe 2.07: d2zvxa_
  • Chain 'B':
    Compound: pancreatic trypsin inhibitor
    Species: Bos taurus [TaxId:9913]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00974 (0-End)
      • engineered (13)
      • engineered (29)
      • engineered (37)
      • engineered (50-51)
    Domains in SCOPe 2.07: d2zvxb_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2zvxA (A:)
    rpdfcleppytgpgkariiryfynakaglaqtfvyggvrakrnnfksaedalrtcgga
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2zvxB (B:)
    rpdfcleppytgpgkariiryfynakaglaqtfvyggvrakrnnfksaedalrtcgga
    

    Sequence, based on observed residues (ATOM records): (download)
    >2zvxB (B:)
    rpdfcleppytgpgkariiryfynakaglaqtfvyggvrakrnnfksaedalrtcgg