PDB entry 2zvj
View 2zvj on RCSB PDB site
Description: Crystal structures of rat Catechol-O-Methyltransferase complexed with coumarine-based inhibitor
Class: transferase
Keywords: Transferase, Methyltransferase, Neurotransmitter degradation, Alternative initiation, Catecholamine metabolism, Cell membrane, Cytoplasm, Magnesium, Membrane, Metal-binding, Phosphoprotein, S-adenosyl-L-methionine, Signal-anchor, Transmembrane
Deposited on
2008-11-07, released
2009-01-06
The last revision prior to the SCOPe 2.06 freeze date was dated
2009-01-06, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.219
AEROSPACI score: 0.35
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Catechol O-methyltransferase
Species: Rattus norvegicus [TaxId:10116]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2zvja_ - Heterogens: MG, SAM, KOM, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2zvjA (A:)
gsmgdtkeqrilryvqqnakpgdpqsvleaidtyctqkewamnvgdakgqimdavireys
pslvlelgaycgysavrmarllqpgarlltmemnpdyaaitqqmlnfaglqdkvtilnga
sqdlipqlkkkydvdtldmvfldhwkdrylpdtlllekcgllrkgtvlladnvivpgtpd
flayvrgsssfecthyssyleymkvvdglekaiyqgpsspdks
Sequence, based on observed residues (ATOM records): (download)
>2zvjA (A:)
dtkeqrilryvqqnakpgdpqsvleaidtyctqkewamnvgdakgqimdavireyspslv
lelgaycgysavrmarllqpgarlltmemnpdyaaitqqmlnfaglqdkvtilngasqdl
ipqlkkkydvdtldmvfldhwkdrylpdtlllekcgllrkgtvlladnvivpgtpdflay
vrgsssfecthyssyleymkvvdglekaiyqg