PDB entry 2zv6

View 2zv6 on RCSB PDB site
Description: Crystal structure of human squamous cell carcinoma antigen 1
Class: hydrolase inhibitor
Keywords: serine proteinase inhibitor, reactive site loop, Acetylation, Alternative splicing, Cytoplasm, Polymorphism, Protease inhibitor, Serine protease inhibitor, HYDROLASE INHIBITOR
Deposited on 2008-11-01, released 2009-02-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-03-03, with a file datestamp of 2009-02-27.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.19
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serpin B3
    Species: Homo sapiens [TaxId:9606]
    Gene: SERPINB3, SCCA, SCCA1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2zv6a_
  • Chain 'B':
    Compound: Serpin B3
    Species: Homo sapiens [TaxId:9606]
    Gene: SERPINB3, SCCA, SCCA1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29508 (12-400)
      • expression tag (11)
    Domains in SCOPe 2.08: d2zv6b1, d2zv6b2
  • Chain 'C':
    Compound: Serpin B3
    Species: Homo sapiens [TaxId:9606]
    Gene: SERPINB3, SCCA, SCCA1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29508 (12-400)
      • expression tag (11)
    Domains in SCOPe 2.08: d2zv6c1, d2zv6c2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2zv6A (A:)
mrgshhhhhhgsnslseantkfmfdlfqqfrkskennifyspisitsalgmvllgakdnt
aqqikkvlhfdqvtenttgkaatyhvdrsgnvhhqfqklltefnkstdayelkianklfg
ektylflqeyldaikkfyqtsvesvdfanapeesrkkinswvesqtnekiknlipegnig
snttlvlvnaiyfkgqwekkfnkedtkeekfwpnkntyksiqmmrqytsfhfasledvqa
kvleipykgkdlsmivllpneidglqkleekltaeklmewtslqnmretrvdlhlprfkv
eesydlkdtlrtmgmvdifngdadlsgmtgsrglvlsgvlhkafvevteegaeaaaatav
vgfgssptstneefhcnhpflffirqnktnsilfygrfssp

    Sequence, based on observed residues (ATOM records): (download) 
    >2zv6A (A:)
nslseantkfmfdlfqqfrkskennifyspisitsalgmvllgakdntaqqikkvlhfnv
hhqfqklltefnkstdayelkianklfgektylflqeyldaikkfyqtsvesvdfanape
esrkkinswvesqtnekiknlipegnigsnttlvlvnaiyfkgqwekkfnkedtkeekfw
pnkntyksiqmmrqytsfhfasledvqakvleipykgkdlsmivllpneidglqkleekl
taeklmewtslqnmretrvdlhlprfkveesydlkdtlrtmgmvdifngdadlsgmtgsr
glvlsgvlhkafvevteegneefhcnhpflffirqnktnsilfygrfssp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2zv6B (B:)
mrgshhhhhhgsnslseantkfmfdlfqqfrkskennifyspisitsalgmvllgakdnt
aqqikkvlhfdqvtenttgkaatyhvdrsgnvhhqfqklltefnkstdayelkianklfg
ektylflqeyldaikkfyqtsvesvdfanapeesrkkinswvesqtnekiknlipegnig
snttlvlvnaiyfkgqwekkfnkedtkeekfwpnkntyksiqmmrqytsfhfasledvqa
kvleipykgkdlsmivllpneidglqkleekltaeklmewtslqnmretrvdlhlprfkv
eesydlkdtlrtmgmvdifngdadlsgmtgsrglvlsgvlhkafvevteegaeaaaatav
vgfgssptstneefhcnhpflffirqnktnsilfygrfssp

    Sequence, based on observed residues (ATOM records): (download) 
    >2zv6B (B:)
snslseantkfmfdlfqqfrkskennifyspisitsalgmvllgakdntaqqikkvlhfd
qvhhqfqklltefnkstdayelkianklfgektylflqeyldaikkfyqtsvesvdfana
peesrkkinswvesqtnekiknlipegnigsnttlvlvnaiyfkgqwekkfnkedtkeek
fwpnkntyksiqmmrqytsfhfasledvqakvleipykgkdlsmivllpneidglqklee
kltaeklmewtslqnmretrvdlhlprfkveesydlkdtlrtmgmvdifngdadlsgmtg
srglvlsgvlhkafvevteegaeaaaatavvgfgssptstneefhcnhpflffirqnktn
silfygrfssp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2zv6C (C:)
mrgshhhhhhgsnslseantkfmfdlfqqfrkskennifyspisitsalgmvllgakdnt
aqqikkvlhfdqvtenttgkaatyhvdrsgnvhhqfqklltefnkstdayelkianklfg
ektylflqeyldaikkfyqtsvesvdfanapeesrkkinswvesqtnekiknlipegnig
snttlvlvnaiyfkgqwekkfnkedtkeekfwpnkntyksiqmmrqytsfhfasledvqa
kvleipykgkdlsmivllpneidglqkleekltaeklmewtslqnmretrvdlhlprfkv
eesydlkdtlrtmgmvdifngdadlsgmtgsrglvlsgvlhkafvevteegaeaaaatav
vgfgssptstneefhcnhpflffirqnktnsilfygrfssp

    Sequence, based on observed residues (ATOM records): (download) 
    >2zv6C (C:)
snslseantkfmfdlfqqfrkskennifyspisitsalgmvllgakdntaqqikkvlhfv
hhqfqklltefnkstdayelkianklfgektylflqeyldaikkfyqtsvesvdfanape
esrkkinswvesqtnekiknlipegnigsnttlvlvnaiyfkgqwekkfnkedtkeekfw
pnkntyksiqmmrqytsfhfasledvqakvleipykgkdlsmivllpneidglqkleekl
taeklmewtslqnmretrvdlhlprfkveesydlkdtlrtmgmvdifngdadlsgmtgsr
glvlsgvlhkafvevteegneefhcnhpflffirqnktnsilfygrfssp