PDB entry 2zv2

View 2zv2 on RCSB PDB site
Description: Crystal structure of human calcium/calmodulin-dependent protein kinase kinase 2, beta, CaMKK2 kinase domain in complex with STO-609
Class: transferase/transferase inhibitor
Keywords: calcium/calmodulin-dependent protein kinase kinase 2, beta, STO-609, CaMKK2, E.C.2.7.11.17, Phosphorylation, AMPKK, metabolism, ATP-binding, kinase, Calmodulin-binding, Nucleotide-binding, Phosphoprotein, Serine/threonine-protein kinase, Transferase, Structural Genomics, NPPSFA, National Project on Protein Structural and Functional Analyses, RIKEN Structural Genomics/Proteomics Initiative, RSGI, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2008-10-31, released 2009-11-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-11-20, with a file datestamp of 2013-11-15.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.203
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Calcium/calmodulin-dependent protein kinase kinase 2
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q96RR4 (Start-297)
  Domains in SCOPe 2.07: d2zv2a_
• Heterogens: 609, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >2zv2A (A:)
  gssgssgdcvqlnqytlkdeigkgsygvvklaynendntyyamkvlskkklirqagfprr
  ppprgtrpapggciqprgpieqvyqeiailkkldhpnvvklvevlddpnedhlymvfelv
  nqgpvmevptlkplsedqarfyfqdlikgieylhyqkiihrdikpsnllvgedghikiad
  fgvsnefkgsdallsntvgtpafmapeslsetrkifsgkaldvwamgvtlycfvfgqcpf
  mderimclhskiksqalefpdqpdiaedlkdlitrmldknpesrivvpeiklhpwvtr
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >2zv2A (A:)
  vqlnqytlkdeigkygvvklaynendntyyamkvlskkeqvyqeiailkkldhpnvvklv
  evlddpnedhlymvfelvnqgpvmevptlkplsedqarfyfqdlikgieylhyqkiihrd
  ikpsnllvgedghikiadfgvsnefkgsdallsntvgtpafmapeslsetrkifsgkald
  vwamgvtlycfvfgqcpfmderimclhskiksqalefpdqpdiaedlkdlitrmldknpe
  srivvpeiklhpwvtr