PDB entry 2ztw

View 2ztw on RCSB PDB site
Description: Structure of 3-isopropylmalate dehydrogenase in complex with the inhibitor and NAD+
Class: oxidoreductase
Keywords: 3-isopropylmalate dehydrogenase, IPMDH, decarboxylating dehydrogenase, Leucine biosynthesis, Amino-acid biosynthesis, Branched-chain amino acid biosynthesis, Cytoplasm, Magnesium, Manganese, Metal-binding, NAD, Oxidoreductase
Deposited on 2008-10-10, released 2009-10-13
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-11-17, with a file datestamp of 2009-11-13.
Experiment type: XRAY
Resolution: 2.79 Å
R-factor: 0.2
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-isopropylmalate dehydrogenase
    Species: Thermus thermophilus [TaxId:274]
    Gene: leuB, TTHA1230
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2ztwa_
  • Heterogens: NAD, DEI, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ztwA (A:)
mkvavlpgdgigpevteaalkvlraldeaeglglayevfpfggaaidafgepfpeptrkg
veeaeavllgsvggpkwdglprkirpetgllslrksqdlfanlrpakvfpglerlsplke
eiargvdvlivreltggiyfgeprgmseaeawnteryskpevervarvafeaarkrrkhv
vsvdkanvlevgefwrktveevgrgypdvalehqyvdamamhlvrsparfdvvvtgnifg
dilsdlasvlpgslgllpsaslgrgtpvfepvhgsapdiagkgianptaailsaammleh
afglvelarkvedavakalletpppdlggsagteaftatvlrhla