PDB entry 2zp0

View 2zp0 on RCSB PDB site
Description: Human factor viia-tissue factor complexed with benzylsulfonamide-D-ile-gln-P-aminobenzamidine
Class: hydrolase/blood clotting
Keywords: SERINE PROTEASE, Blood coagulation, Cleavage on pair of basic residues, Disease mutation, EGF-like domain, Gamma-carboxyglutamic acid, Glycoprotein, Hydrolase, Hydroxylation, Protease, Zymogen, Lipoprotein, Membrane, Palmitate, Transmembrane, HYDROLASE-BLOOD CLOTTING COMPLEX
Deposited on 2008-06-20, released 2008-07-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.218
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Factor VII heavy chain
    Species: Homo sapiens [TaxId:9606]
    Gene: F7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2zp0h_
  • Chain 'L':
    Compound: Factor VII light chain
    Species: Homo sapiens [TaxId:9606]
    Gene: F7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2zp0l1, d2zp0l2, d2zp0l3
  • Chain 'T':
    Compound: tissue factor
    Species: Homo sapiens [TaxId:9606]
    Gene: F3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2zp0t1, d2zp0t2
  • Heterogens: BGC, FUC, CA, PI0, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2zp0H (H:)
    ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
    lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
    lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
    sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
    seprpgvllrapfp
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >2zp0L (L:)
    anafleelrpgslereckeeqcsfeeareifkdaertklfwisysdgdqcasspcqnggs
    ckdqlqsyicfclpafegrncethkddqlicvnenggceqycsdhtgtkrscrchegysl
    ladgvsctptveypcgkipilekrnaskpqgr
    

    Sequence, based on observed residues (ATOM records): (download)
    >2zp0L (L:)
    anafleelrpgslereckeeqcsfeeareifkdaertklfwisysdgdqcasspcqnggs
    ckdqlqsyicfclpafegrncethkddqlicvnenggceqycsdhtgtkrscrchegysl
    ladgvsctptveypcgkipile
    

  • Chain 'T':
    Sequence, based on SEQRES records: (download)
    >2zp0T (T:)
    sgttntvaaynltwkstnfktilewepkpvnqvytvqistksgdwkskcfyttdtecdlt
    deivkdvkqtylarvfsypagnvestgsageplyenspeftpyletnlgqptiqsfeqvg
    tkvnvtvedertlvrrnntflslrdvfgkdliytlyywkssssgkktaktntneflidvd
    kgenycfsvqavipsrtvnrkstdspvecmgqekgefr
    

    Sequence, based on observed residues (ATOM records): (download)
    >2zp0T (T:)
    tvaaynltwkstnfktilewepkpvnqvytvqistksgdwkskcfyttdtecdltdeivk
    dvkqtylarvfsypeplyenspeftpyletnlgqptiqsfeqvgtkvnvtvedertlvrr
    nntflslrdvfgkdliytlyywksgkktaktntneflidvdkgenycfsvqavipsrtvn
    rkstdspvecm