PDB entry 2znv

View 2znv on RCSB PDB site
Description: Crystal structure of human AMSH-LP DUB domain in complex with Lys63-linked ubiquitin dimer
Class: HYDROLASE/Signaling Protein
Keywords: protein complex, metal binding protein, Alternative splicing, Hydrolase, Metal-binding, Metalloprotease, Protease, Ubl conjugation pathway, Zinc, Cytoplasm, Nucleus, Phosphoprotein, HYDROLASE/Signaling Protein COMPLEX
Deposited on 2008-05-01, released 2008-09-02
The last revision prior to the SCOP 1.75 freeze date was dated 2008-09-23, with a file datestamp of 2008-09-19.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.185
AEROSPACI score: 0.69 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: AMSH-like protease
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96FJ0 (Start-177)
      • engineered (33)
  • Chain 'B':
    Compound: Ubiquitin
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62991 (0-75)
      • engineered (62)
    Domains in SCOP 1.75: d2znvb1
  • Chain 'C':
    Compound: Ubiquitin
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62991 (0-75)
      • engineered (76)
    Domains in SCOP 1.75: d2znvc1
  • Chain 'D':
    Compound: AMSH-like protease
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96FJ0 (Start-177)
      • engineered (33)
  • Chain 'E':
    Compound: Ubiquitin
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62991 (0-75)
      • engineered (62)
    Domains in SCOP 1.75: d2znve1
  • Chain 'F':
    Compound: Ubiquitin
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2znvf1
  • Heterogens: ZN, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2znvB (B:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqrestlhlvlrlrgg

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2znvC (C:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrggd

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2znvE (E:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqrestlhlvlrlrgg

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2znvF (F:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrggd

    Sequence, based on observed residues (ATOM records): (download) 
    >2znvF (F:)
mqifvktktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyniqk
estlhlv