PDB entry 2znt

View 2znt on RCSB PDB site
Description: Crystal structure of the ligand-binding core of the human ionotropic glutamate receptor, GluR5, in complex with a novel selective agonist, dysiherbaine
Class: membrane protein
Keywords: GluR5, kainate receptor, ligand-binding core, amino acid, agonist, dysiherbaine, Alternative splicing, Cell junction, Glycoprotein, Ion transport, Ionic channel, Membrane, Phosphoprotein, Polymorphism, Postsynaptic cell membrane, RNA editing, Synapse, Transmembrane, Transport, MEMBRANE PROTEIN
Deposited on 2008-05-01, released 2009-05-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-08-16, with a file datestamp of 2017-08-11.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor, ionotropic kainate 1
    Species: Homo sapiens [TaxId:9606]
    Gene: Grik1, Glur5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P39086 (0-114)
      • linker (115-116)
    • Uniprot P39086 (117-End)
    Domains in SCOPe 2.08: d2znta_
  • Heterogens: DYH, BME, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2zntA (A:)
anrtlivttileepyvmyrksdkplygndrfegycldllkelsnilgfiydvklvpdgky
gaqndkgewngmvkelidhradlavapltityvrekvidfskpfmtlgisilyrkgtpid
saddlakqtkieygavrdgstmtffkkskistyekmwafmssrqqtalvrnsdegiqrvl
ttdyallmestsieyvtqrncnltqigglidskgygvgtpigspyrdkitiailqlqeeg
klhmmkekwwrgngcp

    Sequence, based on observed residues (ATOM records): (download) 
    >2zntA (A:)
anrtlivttileepyvmyrksdkplygndrfegycldllkelsnilgfiydvklvpdgky
gaqndkgewngmvkelidhradlavapltityvrekvidfskpfmtlgisilyrkgtpid
saddlakqtkieygavrdgstmtffkkskistyekmwafmssrqqtalvrnsdegiqrvl
ttdyallmestsieyvtqrncnltqigglidskgygvgtpigspyrdkitiailqlqeeg
klhmmkekwwrgngc