PDB entry 2znn

View 2znn on RCSB PDB site
Description: Human PPAR alpha ligand binding domain in complex with a synthetic agonist TIPP703
Class: transcription
Keywords: NUCLEAR RECEPTOR, PROTEIN-LIGAND COMPLEX, PPAR, Activator, DNA-binding, Metal-binding, Nucleus, Receptor, Transcription, Transcription regulation, Zinc-finger
Deposited on 2008-04-30, released 2009-05-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-03-02, with a file datestamp of 2016-02-26.
Experiment type: XRAY
Resolution: 2.01 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peroxisome proliferator-activated receptor alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: PPARA, NR1C1, PPAR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2znna_
  • Heterogens: S44, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2znnA (A:)
gshmtadlkslakriyeaylknfnmnkvkarvilsgkasnnppfvihdmetlcmaektlv
aklvangiqnkeaevrifhccqctsvetvteltefakaipgfanldlndqvtllkygvye
aifamlssvmnkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnalelddsdi
slfvaaiiccgdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmadlrq
lvtehaqlvqiikktesdaalhpllqeiyrdmy

    Sequence, based on observed residues (ATOM records): (download) 
    >2znnA (A:)
dlkslakriyeaylknfnmnkvkarvilspfvihdmetlcmaektlvaklvangnkeaev
rifhccqctsvetvteltefakaipgfanldlndqvtllkygvyeaifamlssvmnkdgm
lvaygngfitreflkslrkpfcdimepkfdfamkfnalelddsdislfvaaiiccgdrpg
llnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmadlrqlvtehaqlvqiikkt
esdaalhpllqeiyrdmy