PDB entry 2znh

View 2znh on RCSB PDB site
Description: Crystal Structure of a Domain-Swapped Serpin Dimer
Class: blood clotting
Keywords: domain-swap, Blood coagulation, Disease mutation, Glycoprotein, Heparin-binding, Protease inhibitor, Secreted, Serine protease inhibitor, Thrombophilia, BLOOD CLOTTING
Deposited on 2008-04-25, released 2008-10-21
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.201
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: antithrombin-III
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2znha_
  • Chain 'B':
    Compound: antithrombin-III
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2znhb_
  • Heterogens: NAG, CIT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2znhA (A:)
    hgspvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfat
    tfyqhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqih
    fffaklncrlyrkankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenae
    qsraainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfy
    kadgescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekelt
    pevlqewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrd
    dlyvsdafhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplnti
    ifmgrvanpcvk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2znhA (A:)
    hgspvdictakprdipmnpmciyrsptnrrvwelskansrfattfyqhladskndndnif
    lsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrsklvs
    anrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnktegritdvi
    pseaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmyqegkfryrr
    vaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldeleemmlvvhmpr
    friedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkaflevneegsea
    aastavviagrslnpnrvtfkanrpflvfirevplntiifmgrvanpc
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2znhB (B:)
    hgspvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfat
    tfyqhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqih
    fffaklncrlyrkankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenae
    qsraainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfy
    kadgescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekelt
    pevlqewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrd
    dlyvsdafhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplnti
    ifmgrvanpcvk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2znhB (B:)
    hgspvdictakprdipmnpmciyrspeatnrrvwelskansrfattfyqhladskndndn
    iflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrssk
    lvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnktegrit
    dvipseaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmyqegkfr
    yrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldeleemmlvvh
    mprfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkaflevneeg
    seaaastavviagrslnpnrvtfkanrpflvfirevplntiifmgrvanpcv