PDB entry 2zmc

View 2zmc on RCSB PDB site
Description: Crystal structure of human mitotic checkpoint kinase Mps1 catalytic domain apo form
Class: transferase
Keywords: Kinase, Mps1, mitosis, ATP-binding, Nucleotide-binding, Phosphoprotein, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase
Deposited on 2008-04-16, released 2008-05-13
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 3.14 Å
R-factor: 0.226
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dual specificity protein kinase TTK
    Species: Homo sapiens [TaxId:9606]
    Gene: TTK, MPS1L1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2zmca_
  • Heterogens: 7PE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2zmcA (A:)
hhhhhhssglvprgsgmketaaakferqhmdspdlgtddddkasssanecisvkgriysi
lkqigsggsskvfqvlnekkqiyaikyvnleeadnqtldsyrneiaylnklqqhsdkiir
lydyeitdqyiymvmecgnidlnswlkkkksidpwerksywknmleavhtihqhgivhsd
lkpanflivdgmlklidfgianqmqpdttsvvkdsqvgtvnymppeaikdmsssrengks
kskispksdvwslgcilyymtygktpfqqiinqisklhaiidpnheiefpdipekdlqdv
lkcclkrdpkqrisipellahpyvqiqthpvnqmakgtteemkyvlgqlvglnspnsilk
aaktlyehysggeshnssssktfekkrgkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2zmcA (A:)
ecisvkgriysilkqigsggsskvfqvlnekkqiyaikyvnleeadnqtldsyrneiayl
nklqqhsdkiirlydyeitdqyiymvmecgnidlnswlkkkksidpwerksywknmleav
htihqhgivhsdlkpanflivdgmlklidfgianqmdsqvgtvnymppeaikdmskispk
sdvwslgcilyymtygktpfqqiinqisklhaiidpnheiefpdipekdlqdvlkcclkr
dpkqrisipellahpyvqiq