PDB entry 2zl9
View 2zl9 on RCSB PDB site
Description: 2-Substituted-16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation and crystal structure
Class: hormone
Keywords: Protein-ligand complex, DNA-binding, Metal-binding, Nucleus, Phosphoprotein, Receptor, Transcription, Transcription regulation, Zinc, Zinc-finger, HORMONE
Deposited on
2008-04-04, released
2008-06-24
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.216
AEROSPACI score: 0.45
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Vitamin D3 receptor
Species: Rattus norvegicus [TaxId:10116]
Gene: Vdr, Nr1i1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2zl9a_ - Chain 'C':
Compound: Coactivator peptide DRIP
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Heterogens: VDA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2zl9A (A:)
gshmgspnsplkdslrpklseeqqhiiailldahhktydptyadfrdfrppvrmdgstgs
vtldlsplsmlphladlvsysiqkvigfakmipgfrdltsddqivllkssaievimlrsn
qsftmddmswdcgsqdykydvtdvskaghtlelieplikfqvglkklnlheeehvllmai
civspdrpgvqdaklveaiqdrlsntlqtyircrhpppgshqlyakmiqkladlrslnee
hskqyrslsfqpensmkltplvlevfgneis
Sequence, based on observed residues (ATOM records): (download)
>2zl9A (A:)
klseeqqhiiailldahhktydptyadfrdfrppvrmplsmlphladlvsysiqkvigfa
kmipgfrdltsddqivllkssaievimlrsnqsftmddmswdcgsqdykydvtdvskagh
tlelieplikfqvglkklnlheeehvllmaicivspdrpgvqdaklveaiqdrlsntlqt
yircrhpppgshqlyakmiqkladlrslneehskqyrslsfqpensmkltplvlevfg
- Chain 'C':
No sequence available.