PDB entry 2zl4

View 2zl4 on RCSB PDB site
Description: Crystal structure of H.pylori ClpP S99A in complex with the peptide AAAA
Class: hydrolase
Keywords: peptide substrate, tetra-ala, Cytoplasm, Hydrolase, Protease, Serine protease
Deposited on 2008-04-02, released 2008-04-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.204
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain '1':
    Compound: Peptide substrate AAAA
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZL4 (0-3)
  • Chain '2':
    Compound: Peptide substrate AAAA
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZL4 (0-3)
  • Chain 'A':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Helicobacter pylori [TaxId:210]
    Gene: CLPP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56156
      • engineered (98)
    Domains in SCOPe 2.08: d2zl4a_
  • Chain 'B':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Helicobacter pylori [TaxId:210]
    Gene: CLPP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56156
      • engineered (98)
    Domains in SCOPe 2.08: d2zl4b_
  • Chain 'C':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Helicobacter pylori [TaxId:210]
    Gene: CLPP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56156
      • engineered (98)
    Domains in SCOPe 2.08: d2zl4c_
  • Chain 'D':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Helicobacter pylori [TaxId:210]
    Gene: CLPP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56156
      • engineered (98)
    Domains in SCOPe 2.08: d2zl4d_
  • Chain 'E':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Helicobacter pylori [TaxId:210]
    Gene: CLPP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56156
      • engineered (98)
    Domains in SCOPe 2.08: d2zl4e_
  • Chain 'F':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Helicobacter pylori [TaxId:210]
    Gene: CLPP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56156
      • engineered (98)
    Domains in SCOPe 2.08: d2zl4f_
  • Chain 'G':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Helicobacter pylori [TaxId:210]
    Gene: CLPP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56156
      • engineered (98)
    Domains in SCOPe 2.08: d2zl4g_
  • Chain 'H':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Helicobacter pylori [TaxId:210]
    Gene: CLPP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56156
      • engineered (98)
    Domains in SCOPe 2.08: d2zl4h_
  • Chain 'I':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Helicobacter pylori [TaxId:210]
    Gene: CLPP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56156
      • engineered (98)
    Domains in SCOPe 2.08: d2zl4i_
  • Chain 'J':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Helicobacter pylori [TaxId:210]
    Gene: CLPP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56156
      • engineered (98)
    Domains in SCOPe 2.08: d2zl4j_
  • Chain 'K':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Helicobacter pylori [TaxId:210]
    Gene: CLPP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56156
      • engineered (98)
    Domains in SCOPe 2.08: d2zl4k_
  • Chain 'L':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Helicobacter pylori [TaxId:210]
    Gene: CLPP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56156
      • engineered (98)
    Domains in SCOPe 2.08: d2zl4l_
  • Chain 'M':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Helicobacter pylori [TaxId:210]
    Gene: CLPP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56156
      • engineered (98)
    Domains in SCOPe 2.08: d2zl4m_
  • Chain 'N':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Helicobacter pylori [TaxId:210]
    Gene: CLPP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56156
      • engineered (98)
    Domains in SCOPe 2.08: d2zl4n_
  • Chain 'O':
    Compound: Peptide substrate AAAA
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZL4 (0-3)
  • Chain 'P':
    Compound: Peptide substrate AAAA
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZL4 (0-3)
  • Chain 'Q':
    Compound: Peptide substrate AAAA
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZL4 (0-3)
  • Chain 'R':
    Compound: Peptide substrate AAAA
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZL4 (0-3)
  • Chain 'S':
    Compound: Peptide substrate AAAA
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZL4 (0-3)
  • Chain 'T':
    Compound: Peptide substrate AAAA
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZL4 (0-3)
  • Chain 'U':
    Compound: Peptide substrate AAAA
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZL4 (0-3)
  • Chain 'V':
    Compound: Peptide substrate AAAA
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZL4 (0-3)
  • Chain 'W':
    Compound: Peptide substrate AAAA
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZL4 (0-3)
  • Chain 'X':
    Compound: Peptide substrate AAAA
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZL4 (0-3)
  • Chain 'Y':
    Compound: Peptide substrate AAAA
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZL4 (0-3)
  • Chain 'Z':
    Compound: Peptide substrate AAAA
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZL4 (0-3)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain '1':
    No sequence available.

  • Chain '2':
    No sequence available.

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2zl4A (A:)
mmgyipyvientdrgersydiysrllkdrivllsgeindsvassivaqllfleaedpekd
iglyinspggvitsglsiydtmnfirpdvsticigqaaamgafllscgakgkrfslphsr
imihqplggaqgqasdieiisneilrlkglmnsilaqnsgqsleqiakdtdrdfymsake
akeyglidkvlqknvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2zl4A (A:)
diysrllkdrivllsgeindsvassivaqllfleaedpekdiglyinspggvitsglsiy
dtmnfirpdvsticigqaaamgafllscgakgkrfslphsrimihqplggaqgqasdiei
isneilrlkglmnsilaqnsgqsleqiakdtdrdfymsakeakeyglidkvlq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2zl4B (B:)
mmgyipyvientdrgersydiysrllkdrivllsgeindsvassivaqllfleaedpekd
iglyinspggvitsglsiydtmnfirpdvsticigqaaamgafllscgakgkrfslphsr
imihqplggaqgqasdieiisneilrlkglmnsilaqnsgqsleqiakdtdrdfymsake
akeyglidkvlqknvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2zl4B (B:)
diysrllkdrivllsgeindsvassivaqllfleaedpekdiglyinspggvitsglsiy
dtmnfirpdvsticigqaaamgafllscgakgkrfslphsrimihqplggaqgqasdiei
isneilrlkglmnsilaqnsgqsleqiakdtdrdfymsakeakeyglidkvlq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2zl4C (C:)
mmgyipyvientdrgersydiysrllkdrivllsgeindsvassivaqllfleaedpekd
iglyinspggvitsglsiydtmnfirpdvsticigqaaamgafllscgakgkrfslphsr
imihqplggaqgqasdieiisneilrlkglmnsilaqnsgqsleqiakdtdrdfymsake
akeyglidkvlqknvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2zl4C (C:)
diysrllkdrivllsgeindsvassivaqllfleaedpekdiglyinspggvitsglsiy
dtmnfirpdvsticigqaaamgafllscgakgkrfslphsrimihqplggaqgqasdiei
isneilrlkglmnsilaqnsgqsleqiakdtdrdfymsakeakeyglidkvlq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2zl4D (D:)
mmgyipyvientdrgersydiysrllkdrivllsgeindsvassivaqllfleaedpekd
iglyinspggvitsglsiydtmnfirpdvsticigqaaamgafllscgakgkrfslphsr
imihqplggaqgqasdieiisneilrlkglmnsilaqnsgqsleqiakdtdrdfymsake
akeyglidkvlqknvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2zl4D (D:)
diysrllkdrivllsgeindsvassivaqllfleaedpekdiglyinspggvitsglsiy
dtmnfirpdvsticigqaaamgafllscgakgkrfslphsrimihqplggaqgqasdiei
isneilrlkglmnsilaqnsgqsleqiakdtdrdfymsakeakeyglidkvlq

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2zl4E (E:)
mmgyipyvientdrgersydiysrllkdrivllsgeindsvassivaqllfleaedpekd
iglyinspggvitsglsiydtmnfirpdvsticigqaaamgafllscgakgkrfslphsr
imihqplggaqgqasdieiisneilrlkglmnsilaqnsgqsleqiakdtdrdfymsake
akeyglidkvlqknvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2zl4E (E:)
diysrllkdrivllsgeindsvassivaqllfleaedpekdiglyinspggvitsglsiy
dtmnfirpdvsticigqaaamgafllscgakgkrfslphsrimihqplggaqgqasdiei
isneilrlkglmnsilaqnsgqsleqiakdtdrdfymsakeakeyglidkvlq

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2zl4F (F:)
mmgyipyvientdrgersydiysrllkdrivllsgeindsvassivaqllfleaedpekd
iglyinspggvitsglsiydtmnfirpdvsticigqaaamgafllscgakgkrfslphsr
imihqplggaqgqasdieiisneilrlkglmnsilaqnsgqsleqiakdtdrdfymsake
akeyglidkvlqknvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2zl4F (F:)
diysrllkdrivllsgeindsvassivaqllfleaedpekdiglyinspggvitsglsiy
dtmnfirpdvsticigqaaamgafllscgakgkrfslphsrimihqplggaqgqasdiei
isneilrlkglmnsilaqnsgqsleqiakdtdrdfymsakeakeyglidkvlq

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2zl4G (G:)
mmgyipyvientdrgersydiysrllkdrivllsgeindsvassivaqllfleaedpekd
iglyinspggvitsglsiydtmnfirpdvsticigqaaamgafllscgakgkrfslphsr
imihqplggaqgqasdieiisneilrlkglmnsilaqnsgqsleqiakdtdrdfymsake
akeyglidkvlqknvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2zl4G (G:)
diysrllkdrivllsgeindsvassivaqllfleaedpekdiglyinspggvitsglsiy
dtmnfirpdvsticigqaaamgafllscgakgkrfslphsrimihqplggaqgqasdiei
isneilrlkglmnsilaqnsgqsleqiakdtdrdfymsakeakeyglidkvlq

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2zl4H (H:)
mmgyipyvientdrgersydiysrllkdrivllsgeindsvassivaqllfleaedpekd
iglyinspggvitsglsiydtmnfirpdvsticigqaaamgafllscgakgkrfslphsr
imihqplggaqgqasdieiisneilrlkglmnsilaqnsgqsleqiakdtdrdfymsake
akeyglidkvlqknvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2zl4H (H:)
diysrllkdrivllsgeindsvassivaqllfleaedpekdiglyinspggvitsglsiy
dtmnfirpdvsticigqaaamgafllscgakgkrfslphsrimihqplggaqgqasdiei
isneilrlkglmnsilaqnsgqsleqiakdtdrdfymsakeakeyglidkvlq

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >2zl4I (I:)
mmgyipyvientdrgersydiysrllkdrivllsgeindsvassivaqllfleaedpekd
iglyinspggvitsglsiydtmnfirpdvsticigqaaamgafllscgakgkrfslphsr
imihqplggaqgqasdieiisneilrlkglmnsilaqnsgqsleqiakdtdrdfymsake
akeyglidkvlqknvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2zl4I (I:)
diysrllkdrivllsgeindsvassivaqllfleaedpekdiglyinspggvitsglsiy
dtmnfirpdvsticigqaaamgafllscgakgkrfslphsrimihqplggaqgqasdiei
isneilrlkglmnsilaqnsgqsleqiakdtdrdfymsakeakeyglidkvlq

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >2zl4J (J:)
mmgyipyvientdrgersydiysrllkdrivllsgeindsvassivaqllfleaedpekd
iglyinspggvitsglsiydtmnfirpdvsticigqaaamgafllscgakgkrfslphsr
imihqplggaqgqasdieiisneilrlkglmnsilaqnsgqsleqiakdtdrdfymsake
akeyglidkvlqknvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2zl4J (J:)
diysrllkdrivllsgeindsvassivaqllfleaedpekdiglyinspggvitsglsiy
dtmnfirpdvsticigqaaamgafllscgakgkrfslphsrimihqplggaqgqasdiei
isneilrlkglmnsilaqnsgqsleqiakdtdrdfymsakeakeyglidkvlq

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >2zl4K (K:)
mmgyipyvientdrgersydiysrllkdrivllsgeindsvassivaqllfleaedpekd
iglyinspggvitsglsiydtmnfirpdvsticigqaaamgafllscgakgkrfslphsr
imihqplggaqgqasdieiisneilrlkglmnsilaqnsgqsleqiakdtdrdfymsake
akeyglidkvlqknvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2zl4K (K:)
diysrllkdrivllsgeindsvassivaqllfleaedpekdiglyinspggvitsglsiy
dtmnfirpdvsticigqaaamgafllscgakgkrfslphsrimihqplggaqgqasdiei
isneilrlkglmnsilaqnsgqsleqiakdtdrdfymsakeakeyglidkvlq

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >2zl4L (L:)
mmgyipyvientdrgersydiysrllkdrivllsgeindsvassivaqllfleaedpekd
iglyinspggvitsglsiydtmnfirpdvsticigqaaamgafllscgakgkrfslphsr
imihqplggaqgqasdieiisneilrlkglmnsilaqnsgqsleqiakdtdrdfymsake
akeyglidkvlqknvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2zl4L (L:)
diysrllkdrivllsgeindsvassivaqllfleaedpekdiglyinspggvitsglsiy
dtmnfirpdvsticigqaaamgafllscgakgkrfslphsrimihqplggaqgqasdiei
isneilrlkglmnsilaqnsgqsleqiakdtdrdfymsakeakeyglidkvlq

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >2zl4M (M:)
mmgyipyvientdrgersydiysrllkdrivllsgeindsvassivaqllfleaedpekd
iglyinspggvitsglsiydtmnfirpdvsticigqaaamgafllscgakgkrfslphsr
imihqplggaqgqasdieiisneilrlkglmnsilaqnsgqsleqiakdtdrdfymsake
akeyglidkvlqknvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2zl4M (M:)
diysrllkdrivllsgeindsvassivaqllfleaedpekdiglyinspggvitsglsiy
dtmnfirpdvsticigqaaamgafllscgakgkrfslphsrimihqplggaqgqasdiei
isneilrlkglmnsilaqnsgqsleqiakdtdrdfymsakeakeyglidkvlq

  • Chain 'N':
    Sequence, based on SEQRES records: (download) 
    >2zl4N (N:)
mmgyipyvientdrgersydiysrllkdrivllsgeindsvassivaqllfleaedpekd
iglyinspggvitsglsiydtmnfirpdvsticigqaaamgafllscgakgkrfslphsr
imihqplggaqgqasdieiisneilrlkglmnsilaqnsgqsleqiakdtdrdfymsake
akeyglidkvlqknvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2zl4N (N:)
diysrllkdrivllsgeindsvassivaqllfleaedpekdiglyinspggvitsglsiy
dtmnfirpdvsticigqaaamgafllscgakgkrfslphsrimihqplggaqgqasdiei
isneilrlkglmnsilaqnsgqsleqiakdtdrdfymsakeakeyglidkvlq

  • Chain 'O':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    No sequence available.

  • Chain 'R':
    No sequence available.

  • Chain 'S':
    No sequence available.

  • Chain 'T':
    No sequence available.

  • Chain 'U':
    No sequence available.

  • Chain 'V':
    No sequence available.

  • Chain 'W':
    No sequence available.

  • Chain 'X':
    No sequence available.

  • Chain 'Y':
    No sequence available.

  • Chain 'Z':
    No sequence available.