PDB entry 2zks

View 2zks on RCSB PDB site
Description: Structural insights into the proteolytic machinery of apoptosis-inducing Granzyme M
Class: hydrolase/hydrolase inhibitor
Keywords: Serine protease, granzyme, Cytolysis, Glycoprotein, Hydrolase, Secreted, Zymogen, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
Deposited on 2008-03-28, released 2009-03-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Granzyme M
    Species: Homo sapiens [TaxId:9606]
    Gene: GZMM, MET1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2zksa_
  • Chain 'C':
    Compound: hGzmM inhibitor
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZKS (Start-4)
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2zksA (A:)
iiggreviphsrpymaslqrngshlcggvlvhpkwvltaahclaqrmaqlrlvlglhtld
spgltfhikaaiqhprykpvpalendlallqldgkvkpsrtirplalpskrqvvaagtrc
smagwglthqggrlsrvlreldlqvldtrmcnnsrfwngslspsmvclaadskdqapckg
dsggplvcgkgrvlagvlsfssrvctdifkppvatavapyvswirkvtgrsalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2zksA (A:)
iiggreviphsrpymaslqrngshlcggvlvhpkwvltaahclaqrmaqlrlvlglhtld
spgltfhikaaiqhprykpvpalendlallqldgkvkpsrtirplalpskrqvvaagtrc
smagwglthqggrlsrvlreldlqvldtrmcnnsrfwngslspsmvclaadskdqapckg
dsggplvcgkgrvlagvlsfssrvctdifkppvatavapyvswirkvtgrs

  • Chain 'C':
    No sequence available.