PDB entry 2zkj

View 2zkj on RCSB PDB site
Description: Crystal structure of human PDK4-ADP complex
Class: transferase
Keywords: protein-nucleotide complex, homodimer, GHKL superfamily, Carbohydrate metabolism, Glucose metabolism, Kinase, Mitochondrion, Phosphoprotein, Transferase, Transit peptide
Deposited on 2008-03-25, released 2008-08-05
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.188
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4
    Species: Homo sapiens [TaxId:9606]
    Gene: PDK4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2zkja1, d2zkja2
  • Chain 'B':
    Compound: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4
    Species: Homo sapiens [TaxId:9606]
    Gene: PDK4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2zkjb1, d2zkjb2
  • Heterogens: MG, ADP, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2zkjA (A:)
asvprevehfsryspsplsmkqlldfgsenacertsfaflrqelpvrlanilkeidilpt
qlvntssvqlvkswyiqslmdlvefhekspddqkalsdfvdtlikvrnrhhnvvptmaqg
iieykdactvdpvtnqnlqyfldrfymnristrmlmnqhilifsdsqtgnpshigsidpn
cdvvavvqdafecsrmlcdqyylsspelkltqvngkfpdqpihivyvpshlhhmlfelfk
namratvehqenqpsltpievivvlgkedltikisdrgggvplriidrlfsytystaptp
vmdnsrnaplagfgyglpisrlyakyfqgdlnlyslsgygtdaiiylkalssesieklpv
fnksafkhyqmsseaddwcipsrepknlakevam

    Sequence, based on observed residues (ATOM records): (download) 
    >2zkjA (A:)
vprevehfsryspsplsmkqlldfgscertsfaflrqelpvrlanilkeidilptqlvnt
ssvqlvkswyiqslmdlvefhekspddqkalsdfvdtlikvrnrhhnvvptmaqgiieyk
dactvdpvtnqnlqyfldrfymnristrmlmnqhilifsshigsidpncdvvavvqdafe
csrmlcdqyylsspelkltqvngkfpdqpihivyvpshlhhmlfelfknamratvehqen
qpsltpievivvlgkedltikisdrgggvplriidrlfsytystaptaplagfgyglpis
rlyakyfqgdlnlyslsgygtdaiiylkalssesieklpvfnksafkhyqddwci

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2zkjB (B:)
asvprevehfsryspsplsmkqlldfgsenacertsfaflrqelpvrlanilkeidilpt
qlvntssvqlvkswyiqslmdlvefhekspddqkalsdfvdtlikvrnrhhnvvptmaqg
iieykdactvdpvtnqnlqyfldrfymnristrmlmnqhilifsdsqtgnpshigsidpn
cdvvavvqdafecsrmlcdqyylsspelkltqvngkfpdqpihivyvpshlhhmlfelfk
namratvehqenqpsltpievivvlgkedltikisdrgggvplriidrlfsytystaptp
vmdnsrnaplagfgyglpisrlyakyfqgdlnlyslsgygtdaiiylkalssesieklpv
fnksafkhyqmsseaddwcipsrepknlakevam

    Sequence, based on observed residues (ATOM records): (download) 
    >2zkjB (B:)
vprevehfsryspsplsmkqlldfgscertsfaflrqelpvrlanilkeidilptqlvnt
ssvqlvkswyiqslmdlvefhekspddqkalsdfvdtlikvrnrhhnvvptmaqgiieyk
dactpvtnqnlqyfldrfymnristrmlmnqhilifsdsqtgnpshigsidpncdvvavv
qdafecsrmlcdqyylsspelkltqvngkfpdqpihivyvpshlhhmlfelfknamratv
ehqenqpsltpievivvlgkedltikisdrgggvplriidrlfsytystaptpvmaplag
fgyglpisrlyakyfqgdlnlyslsgygtdaiiylkalssesieklpvfnksafkhydw